Root-end sealing of adhesive resin

如果根管中存在细菌，则有必要在根尖周手术后逆行填充，以防止细菌从根管渗漏到根尖周组织中。第一项研究的目的是评估4-META/MMA-TBB树脂与牙骨质的粘附性。牙本质与牙本质的微拉伸粘结强度和渗漏水平基本相等，牙本质与牙本质的粘接耐久性无显著差异。第二项研究的目的是评估4-META/MMA-TBB树脂根端密封后染料从根管泄漏的情况。采用4-META/MMA-TBB树脂进行根端充填的长期充填效果优于采用增强氧化锌-丁香酚水泥或高铜汞合金进行逆行根端充填。第三项研究的目的是评估在不同条件下固化的4-META/MMA-TBB树脂表面的炎症。结果表明，空气固化后树脂周围的炎性结缔组织面积比空气阻隔条固化后抛光的树脂周围的结缔组织面积大。因此，4-META/MMA-TBB树脂的固化条件会影响其生物相容性。第四项研究的目的是评估根端密封与传统的逆行根充填技术在有意再植后的愈合效果。4-META/MMA-TBB树脂根端封闭后的骨愈合优于增强氧化锌-丁香酚水泥逆行根充填，并观察高铜汞合金逆行修复后的骨缺损情况。第五项研究的目的是评估根尖切除术后使用4-META/MMA-TBB树脂进行根端密封后的愈合情况。骨再生明显，牙周韧带间隙正常。由此可见，4-META/MMA-TBB rein在根尖周围手术中具有更好的应用潜力。

In the case of the presence of bacteria in the root canals, it is necessary that retrograde filling following periapical surgery prevent the leakage of bacteria from root canals into periapical tissues. The purpose of first study was to evaluate the adhesion of 4-META/MMA-TBB resin to cementum. The micro-tensile bond strength and the leakage levels obtained for the cementum were almost equal to those for the dentin, and no significant difference in durability of adhesion was recognized between dentin and cementum. The purpose of second study was to evaluate that the dye leakage from root canal after root-end sealing using 4-META/MMA-TBB resin. Root-end sealing using 4-META/MMA-TBB resin performed better sealing for long term than retrograde root filling by reinforced zinc oxide-eugenol cement or high copper amalgam alloy. The purpose of third study was to evaluate inflammation at the surfaces of 4-META/MMA-TBB resin cured under various conditions. The results showed that the area of inflammatory connective tissue around the resin cured by exposure to air was larger than that cured by using a strip for air barrier and polished after curing. Thus, the curing conditions of 4-META/MMA-TBB resin influenced biocompatibility. The purpose of fourth study was to evaluate the healing after root-end sealing compared with conventional technique of retrograde root filling following intentional replantation. The bone healing after root-end sealing using 4-META/MMA-TBB resin was better than retrograde root filling using reinforced zinc oxide-eugenol cement, and the bone defect after retrograde using high copper amalgam alloy was observed. The purpose of fifth study was to evaluate the healing after root-end sealing using 4-META/MMA-TBB resin following apicoectomy. The bone regeneration was remarkable and the normal space of the periodontal ligament was observed. It could be concluded that root-end sealing using 4-META/MMA-TBB rein has a better potential in periapical surgery.