Root-end sealing of adhesive resin

粘合树脂根端密封

• 批准号: 13470401
• 负责人: SUGAYA Tsutomu
• 金额: $ 2.82万
• 依托单位: Hokkaido University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2001
• 资助国家: 日本
• 起止时间: 2001 至 2003
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-13470401/
• 关键词: 4-META; MMA-TBB resin; root-end sealing; retrograde filling; adhesion; leakage; apicoectomy; periapical periodontitis; 根尖性歯周炎; アマルガム; 強化型ユージノールセメント; MMA-TBB レジン; root-end seal; 色素漏洩; 接着強さ; 接着耐久性; 微小引っ張り強さ; セメント質; root-end sealant

In the case of the presence of bacteria in the root canals, it is necessary that retrograde filling following periapical surgery prevent the leakage of bacteria from root canals into periapical tissues. The purpose of first study was to evaluate the adhesion of 4-META/MMA-TBB resin to cementum. The micro-tensile bond strength and the leakage levels obtained for the cementum were almost equal to those for the dentin, and no significant difference in durability of adhesion was recognized between dentin and cementum. The purpose of second study was to evaluate that the dye leakage from root canal after root-end sealing using 4-META/MMA-TBB resin. Root-end sealing using 4-META/MMA-TBB resin performed better sealing for long term than retrograde root filling by reinforced zinc oxide-eugenol cement or high copper amalgam alloy. The purpose of third study was to evaluate inflammation at the surfaces of 4-META/MMA-TBB resin cured under various conditions. The results showed that the area of inflammatory connective tissue around the resin cured by exposure to air was larger than that cured by using a strip for air barrier and polished after curing. Thus, the curing conditions of 4-META/MMA-TBB resin influenced biocompatibility. The purpose of fourth study was to evaluate the healing after root-end sealing compared with conventional technique of retrograde root filling following intentional replantation. The bone healing after root-end sealing using 4-META/MMA-TBB resin was better than retrograde root filling using reinforced zinc oxide-eugenol cement, and the bone defect after retrograde using high copper amalgam alloy was observed. The purpose of fifth study was to evaluate the healing after root-end sealing using 4-META/MMA-TBB resin following apicoectomy. The bone regeneration was remarkable and the normal space of the periodontal ligament was observed. It could be concluded that root-end sealing using 4-META/MMA-TBB rein has a better potential in periapical surgery.

在根管中存在细菌的情况下，根尖周手术后的逆行充填必须防止细菌从根管渗漏到根尖周组织中。第一项研究的目的是评价4-Meta/MMA-TBB树脂与牙骨质的粘附性。牙骨质的微拉伸粘结强度和渗漏水平几乎等于牙本质，牙本质和牙骨质之间的粘附耐久性没有显着差异。第二部分研究4-Meta/MMA-TBB树脂封闭根管后染料渗漏情况。4-Meta/MMA-TBB树脂根端封闭的远期封闭效果优于增强型氧化锌丁香油酚水门汀或高铜银汞合金。第三项研究的目的是评价在各种条件下固化的4-Meta/MMA-TBB树脂表面的炎症。结果表明，暴露于空气中固化的树脂周围炎性结缔组织面积大于用条状物作空气屏障并在固化后抛光的树脂周围炎性结缔组织面积。因此，4-Meta/MMA-TBB树脂的固化条件影响生物相容性。第四项研究的目的是评价根端封闭后的愈合情况，并与传统的意向性再植后逆行根充技术进行比较。4-Meta/MMA-TBB树脂根端封闭后骨愈合优于增强型氧化锌丁香油酚水门汀根管充填，高铜银汞合金根管充填后骨缺损明显减少。第五项研究的目的是评价根尖切除术后使用4-Meta/MMA-TBB树脂进行根端封闭后的愈合情况。骨再生明显，牙周膜间隙正常。结论：4-Meta/MMA-TBB树脂封闭根端在根尖周手术中有较好的应用前景。

项目成果

菅谷 勉: "歯根端切除時に4-META/MMA-TBBレジンをroot-end sealantとして用いた場合の臨床成績"日本歯科保存学雑誌. 45・1. 62-67 (2002)

Tsutomu Sugaya：“根端切除术中使用 4-META/MMA-TBB 树脂作为根端密封剂时的临床结果”日本保守牙科杂志 45・1（2002 年）。

Y.TANAKA: "Durability of Adhesion between 4-META/MMA-TBB Resin and Cementum"Dental Materials Journal. 23(印刷中). (2004)

Y.TANAKA：“4-META/MMA-TBB 树脂和牙骨质之间的粘合耐久性”《牙科材料杂志》23（出版中）。

菅谷 勉ほか: "スーパーボンドC&Bを用いたroot-end sealingの臨床"日本歯科評論. 63・10. 131-140 (2003)

Tsutomu Sugaya 等人：“使用 Superbond C&B 进行根端封闭的临床实践”日本牙科评论 63・10（2003 年）。

T.SUGAYA: "Prognosis of Periradicular Surgery using 4-META/MMA-TBB Resin as Root-end sealant"Journal of Dental Research. 82・suppl. 117 (2003)

T.SUGAYA：“使用 4-META/MMA-TBB 树脂作为根端密封剂的根尖周手术的预后”《牙科研究杂志》82・增刊 117（2003 年）。

川村直人, 菅谷 勉ほか: "4-META/MMA-TBBレジンの硬化条件が組織反応に及ぼす影響"日本歯科保存学雑誌. 46・6. 853-859 (2003)

Naoto Kawamura、Tsutomu Sugaya 等：“4-META/MMA-TBB 树脂的固化条件对组织反应的影响”日本保守牙科杂志 46・6（2003 年）。