The development of novel biomedical material having high intensity and water repellence : the synthesis and analysis of the block copolymer having fluoroethylene and aramid segment

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In the medical field, it is well known that polytetrafluoroethylene (PTFE) is applied to artificial vessels due to their low bioactivity. However, one of the clinical problems caused by PTFE is ischemia by twist in living body. We selected the aromatic polyamides (aramids) as another functional material to overcome the problem of the mechanical properties of PTFE. The target of this study is the development of novel artificial vessels by synthesizing the block copolymer containing fluoroethylene and aramid segments.1)The synthesis of the block copolymers containing fluoroethylene and aramid segmentsFirst, a block copolymer was synthesized by low-temperature solution polycondensation of telechelic diamine containing fluoroethylene segments and isophthaloyl chloride [JP Patent 2002-252183 (2002), J.Polym.Sci., Part A : Polym. Chem., 41, 2840 (2003)]. Secondary block copolymers containing chain-controlled aramid and fluoroethylene number-average molecular weight of these copolymers were 1.7×10^4 and 2.0×10^4, respectively. We attempted the preparation of cast films from these copolymers. These films had uniform thickness, but do not have good mechanical properties.2)The analyses of the surface and physical propertiesWe planned the analysis of the surface and physical properties of these copolymers. But we could not evaluate these properties because too much time was taken to synthesize these copolymers and prepare films. It is assumed that it is possible to synthesize the block copolymer having good mechanical properties by distribution adjustment of fluoroethylene and aramid segments. By overcome the problem of mechanical properties, it is expected that these copolymers are applied artificial vessels.