GRK 2804: Women's mental health across the reproductive years

GRK 2804：育龄期妇女的心理健康

• 批准号: 461715178
• 金额: --
• 依托单位: Eberhard Karls Universität Tübingen
• 依托单位国家: 德国
• 项目类别: International Research Training Groups
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/461715178?language=en
• 关键词: GRK; 2804; Women; mental; health

The proposed International Research Training Group (IRTG) assembles scientists from the University of Tübingen and Uppsala University, Sweden. The IRTG strives to enhance interdisciplinary research and education on a topic of high clinical and societal relevance: women’s mental health across the reproductive years. Women undergo hormonal transitions several times throughout their lives that can impact brain plasticity and their cognitive and emotional processes, thus ultimately influencing mental health. During these transition phases (puberty, pregnancy and menopause), the risk of mental illness increases dramatically, especially with regard to affective, anxiety and stress-related disorders. Within our IRTG we aim to better understand the associations between hormonal transition phases and women’s mental health by addressing specific hypotheses in the context of sex hormone variation. We will emphasize on negative and positive valence as many mental disorders are characterized by the so-called emotional bias, that is high levels of negative emotion and/or loss of positive emotional experience. To do so, we will orient all projects along a translational approach to human behavior and (afflicted) mental health. This will enable us to target specific (neuro)biological processes underlying psychopathology in the realm of negative (stress reactivity) and positive valence (reward), and to cover different system levels (from behavior to brain plasticity). Our long-term perspective is to improve prevention, detection and treatment of mental disorders in women. To fulfill this aim, applicants from Tübingen and Uppsala will combine their strong scientific expertise and clinical experience, collaborate across disciplines, jointly collect and analyze research data and most importantly educate young scientists. Since mental health of women involves many aspects that transcend disciplinary boundaries, the applicants have developed a comprehensive and unique qualification program centered on clinically relevant research, international exchange and synergy. We will foster scientific excellence and independence while at the same time guaranteeing maximal support. The qualification program emphasizes innovative aspects such as the systematic integration of digital networks and platforms to allow an intense German-Swedish exchange. Doctoral candidates will be supervised by a German and a Swedish researcher and mentored by German/Swedish teams, enabling them to profit from an elaborate mentoring program. Thus, our IRTG strives to establish a productive and interdisciplinary environment for high-level education of young scientists putting Tübingen and Uppsala at the forefront of research and education in women’s mental health across the reproductive years.

拟议的国际研究培训小组（IRTG）汇集了来自瑞典图宾根大学和乌普萨拉大学的科学家。 IRTG 致力于加强与临床和社会高度相关的主题的跨学科研究和教育：育龄妇女的心理健康。女性一生会经历多次荷尔蒙转变，这会影响大脑可塑性及其认知和情感过程，从而最终影响心理健康。在这些过渡阶段（青春期、怀孕和更年期），患精神疾病的风险急剧增加，尤其是情感、焦虑和压力相关疾病。在我们的 IRTG 中，我们的目标是通过解决性激素变化背景下的具体假设，更好地了解激素过渡阶段与女性心理健康之间的关联。我们将强调消极和积极的效价，因为许多精神障碍的特点是所谓的情绪偏见，即高水平的消极情绪和/或积极情绪体验的丧失。为此，我们将按照人类行为和（受影响的）心理健康的转化方法来定位所有项目。这将使我们能够在负性（压力反应性）和正性效价（奖励）领域瞄准精神病理学基础的特定（神经）生物过程，并涵盖不同的系统水平（从行为到大脑可塑性）。我们的长期目标是改善女性精神障碍的预防、检测和治疗。为了实现这一目标，来自蒂宾根和乌普萨拉的申请者将结合他们强大的科学专业知识和临床经验，跨学科合作，共同收集和分析研究数据，最重要的是教育年轻科学家。由于女性心理健康涉及超越学科界限的许多方面，申请人制定了以临床相关研究、国际交流和协同作用为中心的全面且独特的资格计划。我们将培养科学卓越性和独立性，同时保证最大程度的支持。该资格计划强调创新方面，例如数字网络和平台的系统集成，以实现德国与瑞典之间的激烈交流。博士候选人将由德国和瑞典研究人员监督，并由德国/瑞典团队指导，使他们能够从精心设计的指导计划中受益。因此，我们的 IRTG 致力于为年轻科学家的高水平教育建立一个富有成效的跨学科环境，使图宾根和乌普萨拉处于育龄妇女心理健康研究和教育的前沿。