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Effect of Trans-cranial Magnetic Stimulation on Functional Recovery of Hemiplegia and Motor Learning ; Study Using of Motor Learning Task and Electrophysiological Methods.

经颅磁刺激对偏瘫功能恢复和运动学习的影响；

基本信息

批准号：
15300206
负责人：
KAWAHIRA Kazumi
金额：
$ 5.38万
依托单位：
Kagoshima University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2003
资助国家：
日本
起止时间：
2003 至 2004
项目状态：
已结题

项目摘要

Repetitive voluntary motion of hemiplegic limb in physical training and motor learning are extremely important for the functional recovery of hemiplegic limbs. The purposes of this study were to study the effect of trans-cranial magnetic stimulation(TMS) on functional recovery of hemiplegia and motor learning.1)System was designed to combine the TMS and facilitation techniques. The trigger for beginning of the TMS was detected with laser light switch for the finger movements. Duration from the trigger to the TMS was designed to be variable. The finger movements were inducted using new designed system. Voltage of EMG evoked this system was bigger that in voluntary movement. The duration from the trigger to the finger movement and magnitude of TMS were studied.2)The summative effect of TNS and repetitive facilitation technique on functional recovery of hemiplegia was studied in three patients with chronic stroke. The functional recovery of hemiplegic limb were found in two of three patients3)The study presented here uses a Computerized Motor Skill Analyzer to examine motor learning tasks in the lower limbs. The normal task in the present study involved tracking a figure-eight with a foot marker. Following a limited practice session the subjects were required to perform a task involving mirror- or point-symmetry movement. This paradigm was used in order to elucidate the effect of motor learning obstruction, and revealed that while motor skills improved in the control group, no significant improvement was seen in the learning obstruction groups. Furthermore, the mirror image task impeded motor learning more than the point symmetry task.

肢体训练和运动学习中偏瘫肢体的重复性随意运动对偏瘫肢体的功能恢复至关重要。本研究旨在探讨经颅磁刺激（TMS）对偏瘫患者功能恢复及运动学习的影响。1)系统设计结合了TMS和促进技术。通过手指运动的激光开关来检测TMS开始的触发。从触发到经颅磁刺激的持续时间设计为可变的。使用新设计的系统诱导手指运动。该系统诱发的肌电电压高于自主运动时。研究了从触发到手指运动的持续时间和经颅磁刺激的强度。2)对3例慢性脑卒中偏瘫患者进行TNS联合重复性易化技术对偏瘫功能恢复的综合疗效研究。3例患者中有2例发现偏瘫肢体功能恢复。3)本研究使用计算机化运动技能分析仪检查下肢的运动学习任务。在本研究中，正常的任务是用脚标记跟踪数字8。经过一段有限的练习后，受试者被要求完成一项涉及镜像或点对称运动的任务。这一范式被用来阐明运动学习障碍的影响，结果显示，虽然运动技能在对照组得到改善，但学习障碍组没有明显的改善。此外，镜像任务比点对称任务对运动学习的阻碍更大。