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Efficacy of influenza vaccination in preventing Methicillin-resistant Staphylococcus auresus (MRSA) infection among the institutionalized elderly

流感疫苗接种预防养老院老人耐甲氧西林金黄色葡萄球菌（MRSA）感染的效果

基本信息

批准号：
15590554
负责人：
WASHIO Masakazu
金额：
$ 1.02万
依托单位：
Sapporo Medical University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2003
资助国家：
日本
起止时间：
2003 至 2005
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-15590554/
关键词：
the elderly elderly care facilities influenza vaccine pneumonia hospitalization antibiotics MRSA

项目摘要

1.A case control study was conducted to evaluate the factors related to MRSA infection among the institutionalized elderly in winter months. The institutionalized elderly with MRSA infection showed more severely limited activities of daily living than those without MRSA infection. The residents with antibiotics therapy as well as those with fever (38.0℃+) were more commonly seen in the MRSA group than the non-MRSA group. The proportion of vaccinated residents did not differ between the two groups because both group showed high vaccination rates.2.An ecological study was conducted to evaluate the factors associated with the influenza-related MRSA infection in the elderly care facilities. Compared with the institutions without MRSA infection, bed-ridden residents, influenza infection, influenza-outbreak, pneumonia, and hospitalization of residents were more common among the institutions with MRSA infection. Although there was no difference between two groups, only a small number of encouraged vaccination to a visiting family member or delivery person in both groups. In contrast, both MRSA and non MRSA groups showed high vaccination rates among the institutionalized elderly.3.Influenza vaccines are recommended not only for the institutionalized elderly but also for nursing staffs, visiting family members and delivery people.

1.通过病例对照研究，探讨冬季住院老年人MRSA感染的相关因素。MRSA感染住院老人的日常生活活动受限程度较未感染住院老人严重。MRSA组较非MRSA组多见于抗生素治疗和发热（38.0℃+）患者。两组居民接种疫苗的比例没有差异，因为两组的疫苗接种率都很高。通过生态学研究，对老年护理机构中流感相关MRSA感染的相关因素进行了评价。与未感染MRSA的机构相比，MRSA感染机构中住院患者卧床、流感感染、流感暴发、肺炎和住院患者较多。虽然两组之间没有差异，但两组中只有少量鼓励给来访的家庭成员或送货员接种疫苗。相比之下，MRSA组和非MRSA组在机构老年人中均显示出较高的疫苗接种率。流感疫苗不仅推荐给住在机构里的老年人，而且也推荐给护理人员、来访的家庭成员和接生人员。