Coordination Funds

在这一优先规划（SPP 2330）框架内，大约25个小组将联合起来建立一个跨学科联盟，重点研究原核生物中病毒与宿主的相互作用。近年来，在原核病毒的生物学方面取得了革命性的发现，包括发现病毒可以利用小分子进行群体水平的决策，发现由病毒形成的细胞内分子复合物模糊了原核和真核生物之间的界限，以及在单细胞和多细胞水平上作用的多种新型抗病毒免疫系统。这些突破性的最新发现现在已经引发了对噬菌体生物学的巨大研究兴趣。通过这个SPP，我们将汇集噬菌体研究的跨学科联盟，结合分子微生物学，生物信息学，数学建模，成像技术，结构生物学和生物化学，形成一个德国卓越小组，将以国际竞争的方式引领这一新兴主题。新建立的SPP侧重于病毒组织复杂性的三个尺度：病毒细胞生物学，新的单细胞和多细胞抗病毒防御策略，以及病毒对多物种微生物群落的影响。该联盟的基本目标是在分子水平上以及在微生物群落的背景下了解原核病毒与宿主相互作用的新机制。这将使我们能够解决不同的病毒生活方式对抗病毒策略进化的影响，并最终阐明社区层面的进化军备竞赛。总之，该联盟的共同努力将引领该领域为这些迅速出现的主题发现新概念，并将开辟生物学的新视野，在分子生物学、噬菌体治疗、食品加工和农业方面具有很高的应用潜力。优先规划的成功从根本上取决于建立正确的框架条件。因此，我们申请年会和国际会议（第三年）的组织资金，研讨会的组织资金，学生交流，博士后启动资金，性别平等措施和公共推广模块。协调基金将由协调员、协调委员会和性别平等委员会管理，所有这些都由特别方案局的协调助理提供支助。

In the frame of this priority programme (SPP 2330) approximately 25 groups will unite to build an interdisciplinary consortium focusing on virus-host interaction in prokaryotes. In recent years, revolutionary discoveries on the biology of prokaryotic viruses were made, including the finding that viruses can use small molecules to make group-level decisions, the discovery of intracellular molecular complexes made by viruses that blur the boundary between prokaryotic and eukaryotic life, and the multitude of novel anti-viral immune systems acting at the unicellular and multicellular level. These ground breaking recent discoveries have now sparked an enormous research interest in phage biology. With this SPP, we will bring together an interdisciplinary consortium on phage research, combining molecular microbiology, bioinformatics, mathematical modelling, imaging techniques, structural biology, and biochemistry to form a German excellence group that will spearhead this emerging topic in an internationally competitive manner.The newly established SPP focuses on three scales of complexity of viral organization: viral cell biology, new unicellular and multicellular anti-viral defense strategies, and viral impact on multispecies microbial communities. The fundamental goals of this consortium are the understanding of new mechanisms in prokaryotic virus-host interactions at the molecular level as well as in the context of microbial communities. This will allow us to address the impact of different viral life styles on the evolution of anti-viral strategies and ultimately will shed light on the evolutionary arms race at the community level. Together, the concerted effort of this consortium will lead the field to uncover new concepts for these rapidly emerging topics and will open up new horizons in biology, with high potentials for applications in molecular biology, phage therapy, food processing, and agriculture.The success of a priority program fundamentally depends on the establishment of the right framework conditions. Therefore, we apply for funding for the organization of annual meetings as well as an international conference (3rd year), funding for the organization of workshops, student exchanges, start-up funding for postdocs, gender equality measures and a public outreach module. The coordination funds will be managed by the coordinator, the coordination committee, and a gender equality board - all supported by the coordination assistant of the SPP.