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Computer-aided Diagnosis on Chest Radiograph : Clinical Usefulness of Temporal Subtraction for detection of Interval Changes

胸部 X 光片计算机辅助诊断：时间减法检测间隔变化的临床用途

基本信息

批准号：
15591285
负责人：
ASHIZAWA Kazuto
金额：
$ 1.98万
依托单位：
Nagasaki University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2003
资助国家：
日本
起止时间：
2003 至 2005
项目状态：
已结题

项目摘要

Temporal subtraction scheme, which is one of the computer-aided diagnosis, is the technique by which a previous chest radiograph is subtracted from a current radiograph in order to enhance interval changes. The purpose of this study is to evaluate the usefulness of this scheme on digital chest radiographs for the detection of interval changes in various lesions seen in daily clinical practice.We performed the observer test as a retrospective study. Forty pairs of digital chest radiographs in 20 cases with interval changes including nodular opacity, localized consolidation, diffuse lung opacity and so on, and 20 cases without interval changes were used. Temporal subtraction images were obtained from a commercially available computer-aided diagnosis (CAD) system (Truedia/XR ; Mitsubishi Space Software, Japan). Eight observers provided their confidence levels for the presence or absence of interval changes without and with temporal subtraction. Their confidence levels were represented on … More a 5-point rating scale (5 : definitely absent, 4 : probably absent, 3 : possibly present, 2 : probably present, 1 : definitely present). The diagnostic performance of observers was improved with use of temporal subtraction in less experienced radiologists.We used this scheme in daily clinical work, and evaluated its usefulness prospectively. Radiologists provided their confidence levels for the presence or absence of interval changes without subtraction on a 5-point rating scale. After that they changed their confidence levels with subtraction in needed. Although the majority of the cases in daily clinical practice were normal or showed no interval change, there were not a few cases in which subtraction images alerted radiologists to locations of missed lesions, or suggested that their interpretations were false positive.In conclusion, the temporal subtraction scheme is useful in the detection of interval changes for various lesions seen in daily work, especially for less experienced radiologists. Less

时间减影技术是计算机辅助诊断的一种，它是将前一张胸片从当前胸片中减去以增强间期变化的技术。本研究的目的是评估该方案在数字胸片上检测日常临床实践中各种病变的间隔变化的有用性。采用40对数字化胸片，其中20例有结节性、局限性实变、弥漫性肺影等间隔改变，20例无间隔改变。从市售计算机辅助诊断（CAD）系统（Truedia/XR ; Mitsubishi Space Software，日本）获得时间减影图像。八个观察员提供了他们的置信水平的存在或不存在的时间间隔的变化，没有和时间减法。他们的信心水平被代表在 ...更多信息 5分评定量表（5：肯定不存在，4：可能不存在，3：可能存在，2：可能存在，1：肯定存在）。在经验不足的放射科医生中，使用时间减影可以提高观察者的诊断性能。我们将此方案应用于日常临床工作中，并对其有效性进行了前瞻性评价。放射科医生提供了他们的置信水平的存在或不存在的间隔变化，没有减法的5点评级量表。之后，他们改变了他们的信心水平与减法的需要。虽然大多数情况下，在日常的临床实践中是正常的或没有表现出间隔的变化，也有不少情况下，减影图像提醒放射科医生的位置错过病变，或建议他们的解释是假阳性的结论，时间减影计划是有用的，在检测的间隔变化，在日常工作中看到的各种病变，特别是经验不足的放射科医生。少