Clinical study on the development for pacemaker navigation system of the stomach

胃起搏器导航系统研制的临床研究

• 批准号: 15591373
• 负责人: ITO Masanao
• 金额: $ 2.3万
• 依托单位: Akita University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2003
• 资助国家: 日本
• 起止时间: 2003 至 2004
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-15591373/
• 关键词: electrogastrogram; pacemaker; ナビゲーション

【Background and purpose】The waves of 2.5-3.5cpm measured with electrogastrogram are called electrical control activity (ECA) and has been thought to be an electric activity generated from the gastric pacemaker. However, there is no report that actually identifies the localization of the gastric pacemaker which contain the Cajal neuron cells, the gastric pacemaker has been assumed to be existed on the greater curvature of the stomach. If the location of the gastric pacemaker is assured during operation and maintained, we can get better function of gastric remnant even after partial gastrectomy. So we tried to develop the navigation system that searches the localization of the gastric pacemaker.【Method】1)Examination of the intraoperative electrogastrogram applied to the ethics committee in Akita University and obtained approval.2)Intraoperative electrogastrogram system was designed for the typical wave form of ECA induced directly by the gastric wall obtained from the previous report. Th … More e navigation system, included several kinds of electrode units and real time diagnostic programs to get the localization, was made by the collaboration with the Faculty of Engineering and Resource Science in Akita University.3)After the completion of the intraoperative electrogastrogram system, informed consent about the examination of the Intraoperative electrogastrogram for the patient planned with gastrectomy was obtained. It was confirmed that the waves of 3cpm was observed by transcutaneous electrogastrogram before the operation.4)In the laparotomy, the electrode unit was attached to the surface of the stomach before gastrectomy and the ECA was measured. Data was storaged with the data recorder, transferred to the personal computer and analyzed by the program that was able to diagnose the localization of the gastric pacemaker simultaneously.【Result】Pacemaker navigation system of the stomach was developed. We can get the direction to the gastric pacemaker by attaching the electrode unit to the gastric wall during the abdominal open surgery. The localization of the gastric pacemaker can be identified by measuring this system. Less

【背景与目的】胃电图测量到的2.5-3.5cpm的电波被称为电控制活动（ECA），被认为是胃起搏器产生的电活动。然而，目前还没有报道真正确定含有卡哈尔神经元细胞的胃起搏器的定位，胃起搏器被认为存在于胃大弯处。如果术中确定并维持胃起搏器的位置，即使在胃部分切除术后，残胃也能得到更好的功能。因此我们尝试开发搜索胃起搏器定位的导航系统。【方法】1）术中胃电图提交秋田大学伦理委员会审查并获得批准。2）根据以往报道获得的胃壁直接诱发的ECA典型波形，设计术中胃电图系统。该导航系统包括多种电极单元和用于定位的实时诊断程序，是与秋田大学工程与资源科学学院合作制作的。3）术中胃电图系统完成后，获得了计划进行胃切除术的患者术中胃电图检查的知情同意。术前经皮胃电图证实观察到3cpm的波。4)剖腹手术中，胃切除前将电极单元贴在胃表面，测量ECA。用数据记录仪存储数据，传输至个人计算机并通过程序进行分析，同时诊断胃起搏器的定位。【结果】研制出胃起搏器导航系统。在腹部开放手术中，我们可以通过将电极单元附着在胃壁上来获得胃起搏器的方向。胃起搏器的位置可以通过测量该系统来确定。较少的