课题基金 / 基金详情

Development of evaluation system for artificial organs from the viewpoints of clinical study, engineering, and statistics.

Development of evaluation system for artificial organs from the viewpoints of clinical study, engineering, and statistics.
从临床研究、工程学和统计学的角度开发人造器官评价系统。
批准号:
15591491
负责人:
FUJIMOTO Tetsuo
金额:
$1.6万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2003
资助国家:
日本
项目状态:
已结题
起止时间:
2003 至 2005

项目摘要

项目成果

FUJIMOTO Tetsuo的其他基金

相关文献

中文摘要
翻译
为了从血流动力学的角度评价心室辅助系统、人工心脏瓣膜、动脉人工移植物等人工器官,开发了循环模拟器。进行了一些实验,以证明用于右心室辅助系统的旋转泵和新设计的股动脉假体Y型移植物在模拟器中的特性。结果表明,分支直径确实增加,从而增加了通过移植物的流速。在这项研究中,一个新设计的压力传感器和可膨胀管的临床应用的设计。前者足够小,可以固定在人造器官中,在人造器官中可以测量压力。后者的设计是为了扩大管的直径,作为气管导管和左心室旁路插管。这些发明正在申请专利。此外,还开发了一个新的数据库系统,以便对临床数据进行统计分析。通过对脉搏波传导速度(PWV)等临床数据的实际分析,揭示了PWV增加,死亡风险增加的趋势。模拟器和数据库系统的结合将有助于从临床研究、工程学和统计学的角度对人工器官进行评价。
英文摘要
A circulatory simulator was developed in order to evaluate artificial organs such as ventricular assist systems, artificial heart valves, and arterial prosthetic grafts from the view point of hemodynamics. Some experiments were conducted to demonstrate characteristics of a rotary pump used for a right ventricular assist system and a newly designed aortofemoral prosthetic Y graft in the simulator. As a result, it was revealed that there was definitely an incremental increase in the branch diameter increasing the flow rate through the graft. In this study, a newly designed pressure transducer and an expandable tube for clinical application were devised. The former is enough small to be fixed into artificial organs in which the pressure can be measured. The latter was designed to expand the diameter of the tube as a tracheal tube and a cannula for left ventricular bypass. These inventions are lodging patent applications. In addition, a new database system was developed in order to analyze clinical data statistically. Clinical data including pulse wave velocity (PWV) were analyzed actually by the system and it was revealed the tendency that the risk of the death increases accompanied by increase in PWV as a result. It is supposed that the combination of the simulator and the database system will be useful to evaluate artificial organs from the viewpoints of clinical study, engineering, and statistics.
期刊论文(102)
专著(0)
科研奖励(0)
会议论文
脳動脈瘤の弾性体モデルによる力学的検討
使用脑动脉瘤弹性体模型进行力学研究
DOI: --
发表时间: 2005
期刊: 福祉工学シンポジウム2005講演論文集 05・44
影响因子: --
作者: [関根佑輔, 藤本哲男, 他]
通讯作者: 他
Study on cerebral aneurysm in elastic simulation model
脑动脉瘤弹性模拟模型研究
DOI: --
发表时间: 2005
期刊: Proceedings of the Welfare Engineering Symposium 2005 No.05-44
影响因子: --
作者: [Yusuke Sekine, Tetsuo Fujimoto, et al.]
通讯作者: et al.
DOI: --
发表时间: 2004
期刊: 福祉工学シンポジウム2004講演論文集(日本機械学会) No.04-42
影响因子: --
作者: [臺寛史, 藤本哲男, 他]
通讯作者: 他
Basic flow characteristics of a pulsatile blood pump driven by two different drivers
由两个不同驱动器驱动的脉动血泵的基本流动特性
DOI: --
发表时间: 2005
期刊: Abstract 8^<th> Japanese-Polish Seminar on New Engineering Method Supporting Human Life
影响因子: --
作者: [K.Ito, T.Fujimoto, et al.]
通讯作者: et al.
共 33 条
    Development of newly designed pressure sensor for regenerative medicine and artificial organs
    • 批准号:
      18591561
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.27万
    • 财政年份:
      2006
    • 负责人:
      FUJIMOTO Tetsuo
    • 依托单位:
    Measurement of Rarefied Gas Flow by OPMS (Optical Pressure Measurement System)
    • 批准号:
      08650227
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $1.47万
    • 财政年份:
      1996
    • 负责人:
      FUJIMOTO Tetsuo
    • 依托单位:
    Development of a Two-dimentional Measurement System for Supersonic Flow using LIUVF
    • 批准号:
      04555043
    • 项目类别:
      Grant-in-Aid for Developmental Scientific Research (B)
    • 资助金额:
      $10.5万
    • 财政年份:
      1992
    • 负责人:
      FUJIMOTO Tetsuo
    • 依托单位:
    Visualization and Measuement of Rarefied Gas Flow using LIUFV
    • 批准号:
      03452122
    • 项目类别:
      Grant-in-Aid for General Scientific Research (B)
    • 资助金额:
      $4.61万
    • 财政年份:
      1991
    • 负责人:
      FUJIMOTO Tetsuo
    • 依托单位: