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Evaluation of intraportal blood flow distribution by four dimensional MR blood flow mapping using subsecond MR imaging

使用亚秒级 MR 成像进行四维 MR 血流测绘评估门静脉内血流分布

基本信息

批准号：
17591274
负责人：
ITO Katsuyoshi
金额：
$ 2.37万
依托单位：
Yamaguchi University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2005
资助国家：
日本
起止时间：
2005 至 2006
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-17591274/
关键词：
trueFISP subsecond MRI blood flow mapping portal flow superior mesenteric venous flow splenic venous flow whirled flow tagging pulse 門脈上腸間膜静脈脾静脈

项目摘要

TrueFISP MR imaging using a selective inversion recovery tagging pulse was performed to evaluate the intraportal venous flow distribution from the superior mesenteric vein and the splenic vein. Tagged blood flow into the portal vein was shown as areas of decreased signal intensity in the portal vein. TrueFISP MR images obtained perpendicular to the portal vein allowed three-dimensional observation of intraportal venous flow distribution. In the study of normal subjects, the blood flow from the superior mesenteric vein and the splenic vein formed streamelined flow in the half of the subjects, but it showed whirled flow in the portal vein in the remaining subjects on the trueFISP MR images obtained perpendicular to the portal vein. TrueFISP MR imaging perpendicular to the portal vein achieved high spatial and high contrast resolution imaging and allowed detailed evaluation of the intraportal venous flow distribution. In our analysis, dark inflow signal to the portal vein from the SMV was … More observed in the right side of the portal vein in 71% at the lower portion while it was seen in the central area of the portal vein in 29% and in the right side in 36% at the upper portion on the oblique MR images perpendicular to the portal vein. Dark inflow signal from the SpV was observed in the left side of the portal vein in 79% at the lower portion while it was seen in the central area of the portal vein in 71% at the upper portion. Whirling flow in the portal vein was observed in 57% on the oblique MR images perpendicular to the portal vein while it was not seen on the coronal MR images. Additionally, four-dimensional blood flow mapping can be performed by serial data acquisition using sebsecond ultrafast MR imaging. In patients with cirrhosis or chronic hepatitis, the whirled flow in the portal vein was often observed probably due to the increased splenic venous flow. The whirled flow may also be associated with the anatomical variations of confluent patterns between the splenic vein and the superior mesenteric vein. In evaluating the influence of fasting and food intake for the portal flow dynamics, we revealed that the portal vein was predominantly perfused by the splenic venous flow before meal while it was predominantly perfused by the superior mesenteric venous flow after meal. Additionally, the superior mesenteric venous flow dramatically increased after meal compared with the fasting state while the splenic venous flow decreased in 41%, increased in 31% and showed no change in 28% of the subjects. Less

使用选择性反转恢复标记脉冲进行TrueFISPMR成像，以评价肠系膜上静脉和脾静脉在门静脉内的血流分布。标记的门静脉血流显示为门静脉内信号强度降低的区域。TrueFISPMR图像垂直于门静脉，可以三维观察门静脉内的血流分布。在正常受试者中，一半受试者肠系膜上静脉和脾静脉的血流形成流线型血流，而其余受试者的门静脉血流在与门静脉垂直的真FISPMR图像上显示为漩涡状血流。与门静脉垂直的TrueFISPMR成像获得了高空间分辨率和高对比度成像，并可以详细评估门静脉内的血流分布。在我们的分析中，从SMV到门静脉的暗流信号是…在垂直于门静脉的斜位MR图像上，门静脉位于右侧的占71%，位于门静脉中心区的占29%，位于门静脉上部的占36%。79%的门静脉下段可见左侧SPV暗流信号，71%上段可见门静脉中心区暗信号。在垂直于门静脉的斜位MR图像上，57%的门静脉内可见回旋血流，而在冠状位MR图像上未见此现象。此外，四维血流成像可以通过使用sebSecond超快磁共振成像的连续数据采集来执行。在肝硬变或慢性肝炎患者中，门静脉内常可见漩涡状血流，可能是由于脾静脉血流增加所致。这种漩涡状血流也可能与脾静脉和肠系膜上静脉之间汇合方式的解剖变异有关。在评价禁食和食物摄入量对门静脉血流动力学的影响时，我们发现餐前门静脉以脾静脉血流为主，餐后以肠系膜上静脉血流为主。此外，餐后肠系膜上静脉血流量较空腹时显著增加，脾静脉血流量减少41%，增加31%，28%无变化。较少