Nutritional program using ^<13>C phenylalanine test in living donor liver transplantation

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Liver transplantation from a living donor has been acceptted procedure with excellent results. However, there remain a problem 'small-for-size graft' which sometimes resulted in poor patient and graft survival.Little is known regarding the impact of liver transplantation on amino acid requirements in children. Since plasma levels of the branched-chain amino acids (BCAA) are decreased in the presence of normal levels of the aromatic amino acids after liver transplantation, normalization of hepatic function may not fully correct changes in BCAA metabolism that occur in the pretransplant period. The goal of the present study was to determine total BCAA requirements of children following liver transplantation using 13C phenylalanine test.We investigated 13C phenylalanine test in living donor liver transplantation program.