Laser-induced transient absorption and photoacoustic spectrometer

激光诱导瞬态吸收和光声光谱仪

• 批准号: 465340770
• 金额: --
• 依托单位: Universität Münster
• 依托单位国家: 德国
• 项目类别: Major Research Instrumentation
• 财政年份: 2021
• 资助国家: 德国
• 起止时间: 2020-12-31 至 无数据
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/465340770?language=en
• 关键词: Laser; induced; transient; absorption; photoacoustic

The photophysical investigation of functional materials plays a fundamental role towards an in-depth understanding of excited state properties at (supra)molecular level. For ongoing and future projects at local, national, and international level, state of the art spectrally and temporally resolved characterization methods are required; hence, laser-induced transient absorption spectroscopy needs to be combined with photoacoustic spectroscopy. This will constitute a unique combination that is presently not available in this form, while enabling the detection of non-luminescent states.Measuring the properties of dark excited states from monomeric or aggregated molecules in solutions, homogeneous matrices, fibres, nano- or microparticles with spectral and temporal resolution at variable temperatures poses a particular challenge. This also applies when the excited state properties of photosensitizers, fluorescent or phosphorescent probes need to be assessed with spectral and temporal resolution in culture media, bacteria, organelles and cells. In particular, the specific interactions with matrixial, bacterial and eukaryotic (hosts cells or protozoic parasites) components need to be monitored. This includes photoinduced charge- or energy-transfer processes leading to non-luminescent states with variable lifetimes or to radical ions. These challenges will be overcome with the requested instrumentation, which will enable the detection of such species, besides the quantification of their energy content. This combination of transient absorption and photoacoustic spectroscopies will boost the development of new labelling techniques for molecular bioimaging and phototherapeutic strategies while leading to new concepts for optoelectronics.

功能材料的光物理研究对于深入理解（超）分子水平上的激发态性质起着基础性的作用。对于正在进行的和未来的项目在地方，国家和国际层面，最先进的光谱和时间分辨的表征方法是必需的;因此，激光诱导瞬态吸收光谱需要与光声光谱相结合。这将构成一种独特的组合，目前还没有这种形式，同时能够检测非发光状态。在可变温度下以光谱和时间分辨率测量溶液、均匀基质、纤维、纳米或微米颗粒中单体或聚集分子的暗激发态特性是一个特殊的挑战。这也适用于需要在培养基、细菌、细胞器和细胞中以光谱和时间分辨率评估光敏剂、荧光或磷光探针的激发态性质时。特别是，需要监测与基质、细菌和真核生物（宿主细胞或原生动物寄生虫）组分的特定相互作用。这包括导致具有可变寿命的非发光状态或自由基离子的光致电荷或能量转移过程。这些挑战将通过所需的仪器来克服，除了量化其能量含量之外，还将能够检测此类物质。这种瞬态吸收和光声光谱的结合将促进分子生物成像和光疗策略的新标记技术的发展，同时导致光电子学的新概念。