X-ray Micro-tomography Validation of HRCT-Based Airway Measurements

基于 HRCT 的气道测量的 X 射线显微断层扫描验证

• 批准号: LP0562715
• 负责人: A/Prof Allan Jones
• 金额: $ 19.15万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2006
• 资助国家: 澳大利亚
• 起止时间: 2006-05-11 至 2010-05-10
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP0562715
• 关键词: ray; Micro; tomography; Validation; HRCT

This project brings together a newly emergent modality of microscopy in the form of 3D X-ray micro-tomography (XRMT) along with leading-edge image analysis to develop breakthrough science in respiratory research aimed at improving the reliability of high resolution computed tomography (HRCT). The project will develop novel 3D lung image segmentation protocols, a stereotactic registration program allowing 3D matching of XRCT and HRCT data sets, and a validation protocol for quantitative HRCT analysis of airway disease. These outcomes will allow wider application of HRCT to non-invasively follow the dynamics of pulmonary function.

该项目汇集了一种新兴的显微镜形式，即3D X射线显微断层扫描（XRMT）沿着前沿的图像分析，以发展呼吸研究中的突破性科学，旨在提高高分辨率计算机断层扫描（HRCT）的可靠性。该项目将开发新的3D肺部图像分割协议，立体定位配准程序，允许XRCT和HRCT数据集的3D匹配，以及气道疾病定量HRCT分析的验证协议。这些结果将允许更广泛地应用HRCT无创地跟踪肺功能的动态变化。