A Physicochemical Approach for Optimizing Drug Delivery from BioSilicon

优化 BioSilicon 药物输送的物理化学方法

• 批准号: LP0562379
• 负责人: Prof Clive Prestidge
• 金额: $ 30.36万
• 依托单位: University of South Australia
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2005
• 资助国家: 澳大利亚
• 起止时间: 2005-12-15 至 2008-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP0562379
• 关键词: Physicochemical; Approach; Optimizing; Drug; Delivery

By applying modern techniques and a multidisciplinary approach, this research will develop an understanding of drug loading of BioSiliconTM at a molecular level. This novel class of nano-structured biomaterial has exciting potential for developing a range of controllable drug delivery systems. Existing medical applications of BioSilicon deliver only small molecules for very specialised uses. Current research has not focused on understanding the pore structure and how it can be adapted for special applications. Our research will create new drug delivery systems with many innovative applications in medical, veterinary and bio-diagnostics fields. The medical and socio-economic impacts will be internationally significant.

通过应用现代技术和多学科方法，本研究将在分子水平上了解BioSiliconTM的载药情况。这种新型的纳米结构生物材料具有开发一系列可控药物递送系统的令人兴奋的潜力。BioSilicon的现有医疗应用仅为非常专业的用途提供小分子。目前的研究还没有集中在了解孔结构，以及如何适应特殊的应用。我们的研究将创造新的药物输送系统，在医学，兽医和生物诊断领域具有许多创新应用。医疗和社会经济影响将具有国际意义。