Interfacial Studies of Nanoparticulate Dendrimers for Improved BioPharmaceutical Application

用于改进生物制药应用的纳米颗粒树枝状聚合物的界面研究

• 批准号: LP0455268
• 负责人: Prof Clive Prestidge
• 金额: $ 26.91万
• 依托单位: University of South Australia
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2004
• 资助国家: 澳大利亚
• 起止时间: 2004-09-10 至 2007-09-10
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP0455268
• 关键词: Interfacial; Studies; Nanoparticulate; Dendrimers; Improved

Dendrimers are a novel class of nanoparticles with exciting potential as pharmaceuticals for the prevention of major disease states, e.g. viral and cancer. A colloid and interfacial chemistry approach will be employed to develop an understanding of the mechanisms for the solution to cell transport processes and for optimisation of formulation strategies for delivery vehicles. Significant advances in the development of novel pharmaceutical products will result, with significant social and economic benefits nationally and internationally.

树枝状聚合物是一类新型的纳米颗粒，具有令人兴奋的潜力，作为药物用于预防主要疾病状态，例如病毒和癌症。 将采用胶体和界面化学方法来了解溶液到细胞转运过程的机制，并优化递送载体的制剂策略。 新药品的开发将取得重大进展，在国内和国际上带来重大的社会和经济效益。