Intermetallic Compounds for the Chemoselective Hydrogenation of α,β-Unsaturated Aldehydes

用于 α,β-不饱和醛化学选择性氢化的金属间化合物

• 批准号: 468939127
• 负责人: Professor Dr. Marc Armbrüster
• 金额: --
• 依托单位: National Natural Science Foundation of China
• 依托单位国家: 德国
• 项目类别: Research Grants
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/468939127?language=en
• 关键词: Intermetallic; Compounds; Chemoselective; Hydrogenation; Unsaturated

The selective hydrogenation of α,β-unsaturated aldehydes to allylic alcohols is a key step in the industrial production of fine chemicals, and is also one of the most widely studied chemoselective hydrogenation reactions in fundamental research. This Sino-German joint project aims to achieve highly active and chemoselective intermetallic catalysts for the gas- and liquid-phase hydrogenation of the α,β-unsaturated crotonaldehyde. We propose to establish the intrinsic stabilities and catalytic properties of bulk intermetallic compounds and subsequently transfer the latter to nanostructured, supported intermetallic catalysts. Using the same intermetallic compounds in an unsupported and supported state enables us to study support influences, and thus to establish reliable structure-property relationships. The experimental studies are corroborated by in situ/operando vibrational spectroscopy and quantum chemical calculations. This will bring us in the situation to set up the reaction mechanism and compare it to the experimentally obtained reaction kinetics of the crotonaldehyde hydrogenation. The implementation of the joint project will lay the scientific basis on the controllable synthesis of new intermetallic catalysts and their application in the heterogeneously catalyzed chemoselective hydrogenation of α,β-unsaturated aldehydes to allylic alcohols.

α，β-不饱和醛选择性加氢制备烯丙醇是精细化学品工业生产中的关键步骤，也是基础研究中研究最多的化学选择性加氢反应之一。该中德合作项目旨在获得用于α，β-不饱和巴豆醛气相和液相加氢的高活性和化学选择性金属间化合物催化剂。我们建议建立的内在稳定性和催化性能的散装金属间化合物，并随后将后者转移到纳米结构的，支持的金属间化合物催化剂。使用相同的金属间化合物在无支撑和支持的状态下，使我们能够研究支持的影响，从而建立可靠的结构-性能关系。实验研究证实了原位/operando振动光谱和量子化学计算。这将使我们处于建立反应机理并将其与实验获得的巴豆醛氢化反应动力学进行比较的情况。该合作项目的实施将为新型金属间化合物催化剂的可控合成及其在α，β-不饱和醛非均相催化化学选择加氢制烯丙醇中的应用奠定科学基础。