Analysis on the thymic epithelial cells in the thymus from the rats which were irradiated

大鼠分别接受6Gy和8Gy剂量的辐照。6Gy照射后胸腺重量减轻，在照射后2 ~ 3天内迅速恢复，而8Gy照射后胸腺恢复缓慢，在照射后7 ~ 11天开始恢复。随后的恢复可达对照组胸腺的65%。通过免疫组织化学和RT-PCR对几种细胞因子的分析，分析了胸腺突然变重的机制，表明细胞因子的变化与胸腺恢复密切相关

Rats were irradiated at the dotes of 6Gy or 8Gy. Thymus weights reduced after irradiation and recovered rapidly within 2 to 3 days after irradiation in the case of 6Gy irradiation, while in the 8Gy irradiation thymus recovery were retarded and started to recover on day 7 to 11 after irradiation. Subsequent recovery was up to 65% of control rat thymus. The mechanisms responsible for abrupt thymus weight were analysed immunohistochemically and by RT-PCR analysis on several cytokines, suggesting cytokine changes were intimately related to the thymic recovery