DEVELOPMENT OF NON-RI SENTINEL NAVIGATION SURGERY FOR LUNG CANCER

我们测试了非RI导航手术治疗肺癌的可行性。在这本书里。我们用吲哚青绿(ICG)作为示踪剂。ICG在红外波段有吸收光谱，通过红外摄像(内窥镜)系统进行观察。开胸手术后，直接向肿瘤周围肺组织注射ICG 25 mg/5ml，无需手术观察。登记在案的案件有6起。常规行肺叶切除和全身结节清扫术。未发现淋巴结转移，未发生ICG不良反应。6例患者经红外线摄像机观察切除的淋巴结，均可在多站清楚地观察到ICG状态。可见ICG作为肺癌手术示踪剂的有效性。然而，术中经红外内窥镜观察，仅有1例可检出手征结节染色。我们认为通过结缔组织或胸膜的穿透力仍然不足。此外。提示淋巴流量的改变可能与此有关。现在我们正在研究肺门和纵隔的淋巴结，以了解肺与其他器官的区别，肺门与纵隔的区别，以及肺门与纵隔的区别。

WE TESTED THE FEASIBILITY OF NON-RI NAVIGATION SURGERY FOR LUNG CANCER. IN THE PRESENT SUTDY. WE USED INDOCYANINE GREEN (ICG) AS A TRACER. OBSERVATION WAS PERFORMED THROUGH INFRAED CAMERA (ENDOSCOPE) SYSTEM BECAUSE ICG SHOWS ABSOUPTION SPECTRUM IN INFARED BAND. AFTER THORACOTOMY, 25MG/5ML OF ICG WAS INJECTED INTO LUNG TISSUE SURROUNDING TUMOR DIRECTLY AND OBSERVATION WAS PERFORMED WITHOUT OPERATION PROSEDURE. IN SIX CASES REGISTERED. USUAL LOBECTOMY AND SYSTEMIC NODAL DISSECTION WAS PERFORMED. NO NODAL METASTASIS WAS FOUND AND NO ADVERSE EFFECT OF ICG ADMINISTRATION WAS OCCURRED. BY OBSERVING DESSECTED LYMPH NODES THROUGH INFRARE CAMERA, ICG STATINING WAS CLEARLY OBSERVED AT MULTI-STATION IN ALL OF SIX CASES. THAT SHOWS THE USEFULNESS OF ICG FOR A TRACER OF LUNG CANCER OPERATION.HOWEVER, BY INTRAOPERATIVE OBSERVATION THROUGH INFRAED ENDOSCOPE, WE COULD DETECT HIRAL NODE STAINING ONLY IN ONE CASE. WE SUGGEST THAT THE PENETRATION POWER THROUGH CONNECTIVE TISSUE OR PLEURA IS STILL INSUFFICIENT. IN ADDITION. VARIATION OF LYMPHATIC FLOW BY INDIVISUALS MIGHT BE INVOLVED. NOW WE ARE INVESTIGATING THE LYMPH NODES OF HILUM AND MEDIASTINUM TO KNOW THE DIFFERENCE BETWEEN LUNG AND THE OTHER ORGANS, BETWEEN HILUM AND MEDIASTINUM, AND BY INDIVISUALS.