SII (Secondary somatosensory cortex) can be separated into two areas: Dorsal side of 511 may participate in pain perception

虽然有证据表明次级躯体感觉皮层（SII）对触觉感知和疼痛有反应，但这种反应发生的位置和SII的作用仍然不清楚。我们使用功能磁共振成像来评估动态和静态机械伤害性刺激的活动。动态伤害性刺激激活背侧和腹侧的SII。静态伤害性刺激仅激活背侧。我们的研究结果表明，SII在功能上分为至少两个不同的区域，背侧被激活的疼痛感知和腹侧的SII可能会对触觉刺激的变化作出反应。

Although evidence shows that the secondary somatosensory cortex (SII) responds to tactile perception and pain, the location where this occurs and the role of SII are still unclear. We used functional MRI to evaluate activity in response to dynamic and static mechanical nociceptive stimulation. Dynamic nociceptive stimulation activated dorsal and ventral sides of SII. Static nociceptive stimulation activated only the dorsal side. Our results show that SIi is functionally divided into at least two different areas; the dorsal side is activated in pain perception and the ventral side of SII may react to changing of tactile stimulation.