MEMOIR: A multi-national randomised factorial placebo-controlled trial with embedded mechanism evaluation of memantine and graded motor imagery for complex regional pain syndrome

回忆录：一项多国随机析因安慰剂对照试验，对复杂区域疼痛综合征进行美金刚和分级运动想象的嵌入式机制评估

• 批准号: nhmrc : GNT1163149
• 金额: $ 230.94万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/memoir-multi-national-pain-syndrome/1379278
• 关键词: MEMOIR; multi; national; randomised; factorial

Complex Regional Pain Syndrome is the most distressing and disabling of all chronic pain conditions, 75% report suicidal thoughts. No treatment is supported by high quality evidence meaning that people with Complex Regional Pain Syndrome often seek unproven and dangerous interventions. We have conducted a series of pilot studies on the two most promising interventions for Complex Regional Pain Syndrome. We are now ready to combine them in a randomised controlled trial.

复杂性局部疼痛综合征是所有慢性疼痛疾病中最令人痛苦和致残的，75%的人报告有自杀念头。没有高质量的证据支持任何治疗，这意味着患有复杂区域疼痛综合征的人经常寻求未经证实和危险的干预措施。我们对两种最有希望的复杂区域疼痛综合征干预措施进行了一系列试点研究。我们现在准备在一项随机对照试验中将它们联合收割机结合起来。