Study on the cerebral activity for the visual disorientation of the spatial movement by functional MRI

功能性MRI研究空间运动视觉定向障碍的脑活动

• 批准号: 14571612
• 负责人: MIZUTA Keisuke
• 金额: $ 1.15万
• 依托单位: Gifu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2002
• 资助国家: 日本
• 起止时间: 2002 至 2003
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-14571612/
• 关键词: Functional MRI; brain activity visual stimulation; spatial disorientation; Vertigo; めまい; functional MRI; 空間識失認; 感覚混乱; 視運動刺激; 温度刺激

The central fields of vertigo have not been elucidated. People feel vertiginous sensaton in the condition which the multiple sensation are irrigated. We aimed to elucidate the central mechanism of the central sensational fields of vertigo. For this aim, we examined the activities of the brain during optokinetic stimulation by functional MRI.The conditions of the optokinetic stimulation are three conditions, the first one of the condition is studied with the low speed of the optokinetic stimulation, the second one is with high speed, and the third one is studied with the low speed of the optokinetic stimulation and with the concurrent caloric stimulation. In the functional MRI, the increase of the activities of the superior temporal gyrus including the MT and MST field showed. The domination of the activity was admitted in the right hemisphere. We examined the activities of the brain during the high speed optokinetic stimulation and concurrent stimulation. When the high speed optokinetic stimulation and the concurrent stimulation are given, the activities of the MT and MST field, and parieto-ccipital area increased. We forecast the increase of the activities of the field concerning with the eye movement beside the field with visual recognition in the brain during the high speed optokinetic and concurrent stimulation. The activities of the MT and MST field, and parieto-ccipital area during the high speed optokinetic and concurrent stimulation were greater than those during the low speed optokinetic stimulation. We suppose that the MT and MST field and parieto-ccipital area concern the recognition of the visual spatial movement in the human brain and the central field of vertigo.

眩晕的中心领域还没有被阐明。人在多重感觉被灌注的情况下会产生眩晕感。我们的目的是阐明眩晕的中心感觉场的中心机制。为此，我们用功能性核磁共振检查了光动力刺激时大脑的活动。光动力刺激的条件有三种，第一种是低速光动力刺激的条件，第二种是高速光动力刺激的条件，第三种是低速光动力刺激和热刺激同时进行的条件。在功能MRI上，颞上回包括MT和MST野的活动增加。大脑右半球承认这种活动占主导地位。我们观察了高速光动力刺激和同步刺激时的脑活动。在高速光动力刺激和同步刺激的情况下，颞叶和颞叶皮层以及顶枕区活动增加。我们预测在高速光动力和同步刺激下，脑内具有视觉识别的与视场旁边眼球运动有关的视场活动增加。高速光动力刺激和并发刺激时脑中颞叶、颞叶、顶枕区的活动均大于低速光动力刺激时的活动。我们认为脑后颞叶和颞叶皮层以及顶枕区与人类大脑视觉空间运动的识别和眩晕的中心区域有关。