Lymphatic architecture in head and neck regions.

头部和颈部区域的淋巴结构。

• 批准号: 14571741
• 负责人: FUJIMURA Akira
• 金额: $ 1.79万
• 依托单位: Iwate Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2002
• 资助国家: 日本
• 起止时间: 2002 至 2003
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-14571741/
• 关键词: lymphatic architecture; head and neck; human; adult; fetus; embryology of lymphatic vessel; lymph node; drug delivery route; リンパ管; 構築; 舌; 腫瘍; 転移; 血管新生阻害剤; TNP-470

The lymphatic architecture in human head and neck regions was studied the relationship with regional lymph node, but not studied about each organs. Therefore, the route between the periphery to the regional lymph node and the connection between the regional lymph nodes were only inferenced. We have studied the lymphatic architecture of each organ in head and neck regions by three-dimensional reconstruction method of serial sections. In this project, we could concern the lymphatic architecture in normal tongue, the dynamics of lymphatic architecture of growth of cancer, and dynamic changes after administration of anti-angiogenic agent. We analogized the metastasis to the regional lymph node starts at the initial lymphatics.

人头颈部淋巴构筑与区域淋巴结的关系已有研究，但对各器官的研究尚不多见。因此，仅推断了外周到区域淋巴结的路径和区域淋巴结之间的连接。采用连续切片三维重建方法，对头颈部各器官的淋巴构筑进行了研究。在这个项目中，我们可以关注正常舌的淋巴结构，肿瘤生长过程中淋巴结构的动态变化，以及应用抗血管生成剂后的动态变化。我们类比区域淋巴结的转移始于最初的淋巴管。

项目成果

Toshihiro Ohta, Akira Fujimura: "Changes in architecture of lymphatic vessels around tumor induced by Antiangiogenic agent E7820."Dental Journal of Iwate Medical University. 29(1). 79-92 (2004)

Toshihiro Ohta、Akira Fujimura：“抗血管生成剂 E7820 诱导肿瘤周围淋巴管结构的变化。”岩手医科大学牙科杂志。

大内まりえ, 藤村 朗: "圧迫側歯根膜の血流変化について"岩手医科大学歯学雑誌. 29・1. 1-8 (2004)

大内麻理惠、藤村晃：“压缩牙周膜中的血流变化”岩手医科大学牙科杂志29・1（2004）。

T.Ohta, A.Fujimura: "Changes in architecture of lymphatic vessels around tumor induced by Antiangiogenic agent E7820."Dental Journal of Iwate Medical University. 29・1. 93-102 (2004)

T.Ohta，A.Fujimura：“抗血管生成剂 E7820 诱导的肿瘤周围淋巴管结构的变化”，岩手医科大学牙科杂志 29・1（2004 年）。

Akira Fujimura, et al.: "Three dimensional architecture of lymphatic vessels in the tongue"LYMPHOLOGY. 36(3). 120-127 (2003)

Akira Fujimura 等人：“舌内淋巴管的三维结构”淋巴学。

Shotaro Seki, Akira Fujimura: "Three dimensional changes in lymphatic architecture around VX2 tongue cancer. -Dynamic changes after administration of anti-angiogenic agent-"LYMPHOLOGY. 36(4). 199-208 (2004)

Shotaro Seki、Akira Fujimura：“VX2 舌癌周围淋巴结构的三维变化。-施用抗血管生成剂后的动态变化-”淋巴学。