Development and application of artificial acyltransferase models based on host compounds

主要研究成果如下：1.开发了水溶性功能化脱氢缩合剂的合成工艺; 2.基于18-冠-63的环转移酶模型; 4.开发了胶束中脂肪酸特异性酰基CoA转移酶模型; 5.以液-液两相体系为反应场的底物特异性反应; 6.新型脱氢缩合剂固定化体系，6.利用含氟溶剂合成未保护氨基酸的肽

Following Results are successfully obtained.1.Development of synthetic technology utilizing for the preparation of functionalized dehydrocondensing agents available in water2.Cyclotransferase model based on 18-crown-63.Development of fatty acids-specific acyl CoA transferase models in micelles.4.Substrate-specific reactions utilizing liquid-liquid biphasic system as a reaction field5.Novel immobilizing systems of dehydrocondensing agents, which are useful to utilize enzyme models.6.Peptide synthesis of unprotected amino acids by use of fluorous solvents