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A Research Project for Diagnosis, Treatment and Pathophysiology of Small Intestinal Diseases Using Double-Balloon Endoscopy.

使用双气囊内窥镜检查小肠疾病的诊断、治疗和病理生理学研究项目。

基本信息

批准号：
16590623
负责人：
YAMAMOTO Hironori
金额：
$ 2.24万
依托单位：
JICHI MEDICAL UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2004
资助国家：
日本
起止时间：
2004 至 2005
项目状态：
已结题

项目摘要

We have experienced more than 530 cases of enteroscopy using double-balloon endoscopy by the end of March 2006. From these experiences, we have established the insertion method of double-balloon endoscopy. We also established the therapeutic method in the small intestine, such as hemostasis, polypectomy, balloon dilation, stent placement and retrieval of foreign bodies.We also performed a multi-center trial of a comparison between double-balloon endoscopy and capsule endoscopy in cooperation with Dokkyo University to establish the standard approaching strategy for the small intestinal diseases.We also actively performed endoscopic approaches to a segment of intestinal tracts with surgically altered anatomy, which had been difficult with standard endoscopy, such as an afferent limb of Billroth II or Roux-en-Y reconstruction using double-balloon endoscopy. We established endoscopic billiary treatments with double-balloon endoscopy for such kind of patients.We also performed multi-center … More trials of research on small intestinal diseases in a working group which is composed of Jichi Medical University, Nippon Medical University, Nagoya University, Kyoto University, Hiroshima University, Kyushu University and Fukuoka University. The working group was organized with the core members of the society for the study of small intestinal endoscopy which was established in 2003.We also worked for international education and spreading of double-balloon endoscopy. As a result, double-balloon endoscopy is currently used in more than 33 countries in the world. There are already many publications from Europe, America and Oceania which report usefulness and safety of double-balloon endoscopy. Double-balloon endoscopy has been accepted as a new standard of enteroscopy in an international level. We have organized the 1st International Workshop on Double-Balloon Endoscopy which will be held at Tokyo in August of 2006 to share the experience, standardize the technique and improve our knowledge on small intestinal diseases. International committee of the workshop is composed of delegates from Japan, America, Canada, Germany, Netherlands, China and Korea.Basic research on the small intestine using double-balloon endoscopy is also ongoing. Specifically, a researcher of our division is sent to the department of microbiology in our university for the study of the intestinal bacterial flora. Our first aim is to elucidate the normal bacterial flora of the human small intestine. Less

截至2006年3月底，我们已经经历了超过530例使用双气囊内窥镜的小肠镜检查。根据这些经验，我们建立了双气囊内窥镜的置入方法。建立了小肠止血、息肉切除、球囊扩张、支架置入、异物取回等治疗方法；与大专合作开展了双气囊内窥镜与胶囊内窥镜的多中心对比试验，建立了小肠疾病的标准进路策略；对Billroth II传入肢体或Roux-en-Y重建等常规内窥镜难以手术切除的肠道段，积极实施内窥镜手术入路。对于此类患者，我们建立了双气囊内窥镜胆道治疗方法，并进行了多中心…在由集聚医科大学、日本医科大学、名古屋大学、京都大学、广岛大学、九州大学和福冈大学组成的工作组中，进行了更多关于小肠疾病的研究。工作组由2003年成立的小肠内窥镜研究会的核心成员组成，并致力于双气囊内窥镜的国际教育和推广。因此，双气囊内窥镜目前在世界上超过33个国家使用。欧洲、美洲和大洋洲已经有许多出版物报道了双气囊内窥镜的有效性和安全性。双气囊内窥镜检查已成为国际公认的肠镜检查新标准。我们组织了首届国际双气囊内窥镜研讨会，将于2006年8月在东京举行，分享经验，规范技术，提高我们对小肠疾病的认识。研讨会的国际委员会由来自日本、美国、加拿大、德国、荷兰、中国和韩国的代表组成。双气囊内窥镜对小肠的基础研究也在进行中。具体地说，我们部门的一名研究人员被派往我们大学微生物系研究肠道细菌群。我们的第一个目标是阐明人类小肠的正常细菌菌群。较少