课题基金 / 基金详情

Development of highly sensitive assay for TSH receptor antibody (TRAb) ; simultaneous measurements of TSAb, TSBAb, and TBII

Development of highly sensitive assay for TSH receptor antibody (TRAb) ; simultaneous measurements of TSAb, TSBAb, and TBII
开发高灵敏度 TSH 受体抗体 (TRAb) 检测方法；
批准号：
16590911
负责人：
TAKASU Nobuyuki
金额：
$2.3万
依托单位：
University of the Ryukyus
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2004
资助国家：
日本
项目状态：
已结题
起止时间：
2004 至 2005
来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-16590911/
关键词：
TSAbTSBAbTBIITRAbGraves' diseaseHashimoto's thyroiditishyperthyroidismhypothyroidismTSH受容体TSH受容体抗体超高感度TSAb

项目摘要

项目成果

TAKASU Nobuyuki的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
TSH receptor antibody (TRAb) causes Graves' disease. TSH-binding inhibitor immunoglobulin (TBII) and thyroid stimulating antibody (TSAb) have been measured as TSH receptor antibody (TRAb) to diagnose Graves' disease. TBII is measured as a receptor assay and TSAb as a stimulator assay. TSAb stimulates the thyroid gland and causes Graves' hyperthyroidism. TSAb reflects thyroid stimulating antibody (TSAb)-activity, but TBII does not necessarily do so. TBII may reflect the activity of TSH-stimulation blocking antibody (TSBAb). TSBAb causes hypothyroidism. TBII has been widely used to diagnose Graves' disease.The aim of this study is to develop highly sTSAb (sensitive thyroid-stimulating antibody)-assay. We also intended to develop highly sensitive assay for TSH receptor antibody (TRAb), which would measure TSAb, TSBAb, and TBII, simultaneously.We developed a highly sensitive TSAb (sTSAb) assay. We are now developing new assay to measure TSAb, TSBAb, and TBII, simultaneously.
期刊论文(226)
专著(0)
科研奖励(0)
会议论文
Acute brain injury in hypoglycaemia-induced hemiplegia
DOI： 10.1111/j.1464-5491.2004.01185.x
发表时间： 2004-06-01
期刊： DIABETIC MEDICINE
影响因子： 3.5
作者： [Shirayama, H, Ohshiro, Y, Takasu, N]
通讯作者： Takasu, N
Genome-wide linkage analysis of type 2 diabetes mellitus reconfirms the susceptibility locus on 11p13-p12 in Japanese
DOI： 10.1007/s10038-004-0199-3
发表时间： 2004-11-01
期刊： JOURNAL OF HUMAN GENETICS
影响因子： 3.5
作者： [Nawata, H, Shirasawa, S, Sasazuki, T]
通讯作者： Sasazuki, T
Acute brain injury in hypglycaemia-induced hemiplegia.
低血糖引起的偏瘫中的急性脑损伤。
DOI： --
发表时间： 2004
期刊： Diabet Med 21 (6)
影响因子： --
作者： [Shirayama H, Takasu N]
通讯作者： Takasu N
Sensitive thyroid-stimulating antibody assay with high concent-rations of polyethylene glycol for the diagnosis of Graves' disea
高浓度聚乙二醇敏感促甲状腺抗体检测诊断格雷夫斯病
DOI： --
发表时间： 2004
期刊： Clin Exp Pharmacol Physiol 31(5-6)
影响因子： --
作者： [Takasu N, Kamijo K, Sato Y, Yoshimura H, Nagata A, Ochi Y]
通讯作者： Ochi Y
共 58 条
    Remission of Graves' Hyperthyroidism and CTLA-4-Gene
    • 批准号：
      13671159
    • 项目类别：
      Grant-in-Aid for Scientific Research (C)
    • 资助金额：
      $2.24万
    • 财政年份：
      2001
    • 负责人：
      TAKASU Nobuyuki
    • 依托单位：
      University of the Ryukyus
    Graves' & Hashimoto's diseases and apoptosis
    • 批准号：
      08671175
    • 项目类别：
      Grant-in-Aid for Scientific Research (C)
    • 资助金额：
      $1.47万
    • 财政年份：
      1996
    • 负责人：
      TAKASU Nobuyuki
    • 依托单位：
      University of the Ryukyus
    Molecular mechanisms of the developments of Graves' disease and diabetes mellitus ; O_2 production-DNA damage and their signal transductions
    Signal transduction systems for thyroid cell proliferation and differentiation and their abnormalities in Graves' thyroid cells
    • 批准号：
      62570509
    • 项目类别：
      Grant-in-Aid for General Scientific Research (C)
    • 资助金额：
      $0.32万
    • 财政年份：
      1987
    • 负责人：
      TAKASU Nobuyuki
    • 依托单位：
      Shinshu University School of Medicine
    国内基金
    海外基金
    hTRAb 组合基因文库的建立及单链TSAb,TSBAb分子克隆
    • 批准号：
      39870336
    • 项目类别：
      面上项目
    • 资助金额：
      10.0万元
    • 批准年份：
      1998
    • 负责人：
      陈昆明
    • 依托单位：
      天津医科大学