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A study on manufacture of the liner for artificial joints as human-friendly

人性化人工关节内衬的制造研究

基本信息

批准号：
17560106
负责人：
SHINTANI Kazuhiro
金额：
$ 2.18万
依托单位：
Kanazawa Institute of Technology
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2005
资助国家：
日本
起止时间：
2005 至 2006
项目状态：
已结题

项目摘要

An artificial femoral head was made of a cobalt-chromium alloy (Co-Cr) that has cytotoxicity. And there are need that replace Co-Cr by a high-biocompatible alumina ceramics. However, an alumina ceramics femoral head is not common head material because the alumina ceramics is low-impact material. A cup was an artificial cartilage that made of ultrahigh-molecule weight polyethylene (UHMWPE). In last time, it was reported that a foamed UHMWPE has impact cushion ability. And the report showed the possibility that can use an artificial femoral head made of a high-biocompatible alumina ceramics. This research performs development of the wear control, the impact absorption, and the damage prevention mechanism of the UHMWPE liner regarded as the cause of artificial joint re-substitution in the femur in plant system. Construction of the optimal processing method about liner fabrication was considered. Moreover, as a result of carrying out a friction examination, it showed clearly to control the wear powder of a liner by giving a DLC film and a hybrid nano diamond (HND) film. Furthermore, it also showed clearly to acquire sufficient durability after 300,000 friction experiments in the thickness of 500nm. On the other hand, the U.H.M.W.P.E. foaming liner was manufactured and the impact absorption of this material was examined. The maximum impulse force and the amount of plastic deformation have the relation of an inverse proportion, and it showed clearly for the optimum foaming rate of a liner to be 80%. Furthermore, skin layer about 1mm was obtained on this condition. On the other hand, manufacture of the liner suitable for the size and form of patient each has not been performed in fact. However, the creation of affected part form data and CAD data carried out based on picture information was completed.

人工股骨头由具有细胞毒性的钴铬合金（Co-Cr）制成。并且需要用高生物相容性的氧化铝陶瓷代替Co-Cr。然而，氧化铝陶瓷股骨头不是常见的股骨头材料，因为氧化铝陶瓷是低冲击材料。髋臼杯是由超高分子量聚乙烯（UHMWPE）制成的人工软骨。上次报告称，发泡UHMWPE具有冲击缓冲能力。该报告显示了使用高生物相容性氧化铝陶瓷制成的人工股骨头的可能性。本研究对UHMWPE内衬的磨损控制、冲击吸收和损伤预防机制进行了开发，认为UHMWPE内衬是植入系统中股骨人工关节再次置换的原因。研究了药型罩制造的最佳工艺方法。此外，作为进行摩擦检验的结果，清楚地表明通过提供DLC膜和混合纳米金刚石（HND）膜来控制衬垫的磨损粉末。此外，在500 nm的厚度下进行30万次摩擦实验后，也清楚地显示出获得了足够的耐久性。另一方面，UHMWPE制造发泡衬垫，并检测该材料的冲击吸收。最大冲击力与塑性变形量成反比关系，表明衬板的最佳发泡率为80%。在此条件下，获得了约1 mm的表皮层。另一方面，实际上还没有进行适合于患者的尺寸和形状的内衬的制造。但是，基于图片信息进行的受影响部分形状数据和CAD数据的创建已经完成。