How do effector proteins from necrotrophic fungi cause disease in plants?

该项目旨在开发新的知识，以支持制定保护小麦免受坏死性真菌侵染的策略。在一个对粮食、纤维和生物燃料的需求日益增加的世界里，植物病害造成的作物损失是一个重大的经济、环境和社会挑战。小麦白僵菌是一种重要的小麦坏死性真菌病原菌。在感染过程中，P.nodorum使用效应蛋白来靶向小麦中的敏感基因产物。这一过程被称为坏死营养效应触发的敏感性，导致植物细胞死亡和疾病。本课题旨在研究小麦黑星病致病效应触发的感病机制的结构基础。

This project aims to develop new knowledge to support the development of strategies to protect wheat from necrotrophic fungi. Crop losses caused by plant diseases are a significant economic, environmental and social challenge in a world facing increased demands on food, fibre and biofuels. Parastagonospora nodorum is an economically important necrotrophic fungal pathogen of wheat. During infection, P. nodorum uses effector proteins to target sensitivity gene products in wheat. This process, known as necrotrophic effector-triggered susceptibility, results in plant cell death and disease. This project aims to investigate the structural basis of necrotrophic effector-triggered susceptibility in the P. nodorum – wheat pathosystem.