Understanding the molecular basis of fungal rust diseases in plants

了解植物真菌锈病的分子基础

• 批准号: FT200100135
• 负责人: Dr Simon Williams
• 金额: $ 54.47万
• 依托单位: The Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: ARC Future Fellowships
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-11-23 至 2024-12-22
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FT200100135
• 关键词: Understanding; molecular; basis; fungal; rust

This project aims to utilise structural biology, biochemistry and molecular biology approaches to substantially deepen our understanding of rust fungi-plant interactions. Fungal rust pathogens cause disease and significant yield losses in our most important food crops. During colonisation, rust fungi utilise secreted effector proteins to cause plant disease. Effectors can also be recognised by plant immunity receptors, leading to resistance. The intended outcome of this work is to generate knowledge that can be used for the development of disease management and engineering strategies to protect plants from rust fungi. This should provide significant benefits to agricultural productivity and global food security.

该项目旨在利用结构生物学、生物化学和分子生物学方法，大大加深我们对锈菌-植物相互作用的理解。真菌锈菌病原体在我们最重要的粮食作物中引起疾病和显著的产量损失。在定殖期间，锈菌利用分泌的效应蛋白引起植物病害。效应子也可以被植物免疫受体识别，导致抗性。这项工作的预期成果是产生知识，可用于疾病管理和工程策略的发展，以保护植物免受锈菌。这将为农业生产力和全球粮食安全带来重大惠益。