The hidden potential of South American Cortinarii

南美 Cortinarii 的隐藏潜力

• 批准号: 491871566
• 负责人: Dr. Norbert Arnold
• 金额: --
• 依托单位: Abteilung Natur- und Wirkstoffchemie
• 依托单位国家: 德国
• 项目类别: Research Grants
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/491871566?language=en
• 关键词: hidden; potential; South; American; Cortinarii

The aim of the project is to sample and eventually newly describe South American dermocyboid C., to isolate, identify their pigments, and to test the latter for photo-activity. As a base of the project, the taxonomy of endemic dermocyboid Cortinarii is resolved with extensive fieldwork, molecular network analysis of metabolites, and multi-gene phylogeny. Molecular network analysis is used for the first time here as metabolomic-taxonomical tool. Pigment profiles will be created by coupling thin layer chromatography and mass spectrometry using desorption electrospray ionization. (New) pigments will be isolated and their structure elucidated and tested for their biological activity with a focus on targeted light activation.

该项目的目的是采样并最终新描述南美dermocyboid C.，分离、鉴定它们的色素，并测试后者的光活性。作为该项目的基础，本研究通过野外调查、代谢产物的分子网络分析和多基因同源性分析，解决了地方性皮虫科氏虫的分类问题。分子网络分析在这里首次被用作代谢组学分类学工具。将使用解吸电喷雾电离通过耦合薄层色谱法和质谱法创建色素谱。(New)色素将被分离出来，其结构将被阐明，其生物活性将被测试，重点是目标光激活。