Health Behaviour of persons with Multiple Sclerosis in Germany: Current status and development of supportive strategies for smoking cessation and dietary behaviour change (BEHAVIMS)

多发性硬化症（MS）是一种慢性神经系统疾病，其表现基于遗传易感性和环境因素，导致至少三分之二的MS患者严重残疾。健康行为，如体育活动，不吸烟和饮食有可能对MS病程产生积极影响。然而，人们对MS患者的实际健康行为缺乏了解。此外，迄今为止，德国尚未将健康行为的循证管理纳入MS临床护理，而患者的兴趣很高。我们的项目旨在缩小研究差距，并解决MS中两个重要的健康行为：吸烟和饮食习惯。具体来说，我们的项目追求以下四个目标：1。描述两种不同患者群体中多发性硬化症患者的健康行为：德国人口代表性的NAKO gesundheits研究和来自大学医院多发性硬化症日间诊所的临床样本。这里的一个特别目的是澄清在评估多发性硬化症患者的健康行为时，大学队列在多大程度上具有代表性。根据需求评估和德国广泛建立的针对一般人群的评估项目“Rauchfrei”，为MS患者制定在线戒烟干预措施。3. 通过为多发性硬化症患者制定循证患者信息和饮食决策帮助，促进食品素养和知情决策。开发一种用于多发性硬化症患者饮食评估的筛选工具和食品素养问卷，用于临床研究和护理。

Multiple sclerosis (MS) is a chronic neurological condition which manifests based on genetic vulnerability coupled with environmental factors leading to substantial disability in at least two thirds of persons with MS. Health behaviours like physical activity, non-smoking and diet have the potential to impact positively on MS disease course. However, there is a lack of knowledge about the actual health behaviour of persons with MS. Moreover, evidence-based management of health behaviours is not integrated into clinical MS care in Germany to date, while the interest of patients is high. Our project aims to close research gaps and address two important health behaviours in MS: Tobacco smoking and dietary habits. Specifically, our project pursues the following four objectives: 1. Description of the health behaviour of persons with MS in two different patient populations: The German population-representative NAKO Gesundheitsstudie and a clinical sample from the MS Day Clinic of a university hospital. A special aim here is to clarify to which extent a university cohort is representative in assessing health behaviours in MS. 2. Develop an online smoking cessation intervention for persons with MS based on a needs assessment and the Germany wide established evaluated programme “Rauchfrei” for the general population. 3. Promote food literacy and informed decisions by developing an evidence-based patient information and decision aid on diet for persons with MS. 4. Develop a screening tool for dietary assessment and a food literacy questionnaire in MS to be used in clinical research and care.