Disorganization of cell and tissue systems in cancer

以前的一些研究揭示了癌细胞在基因和细胞水平上的特性，有助于阐明癌症是一种威胁生命的疾病的机制。在积累了一系列关于癌细胞的证据的基础上，本项目系统地研究了如何根据癌症中细胞和组织系统的破坏来诱导癌症的发生和发展。研究发现，癌细胞的运动、增殖和黏附的异常在这种紊乱中起着重要作用。

A number of previous studies revealed the properties of cancer cells at the levels of genes and cells, contributing to the elucidation of the mechanisms by which cancer is a life-threatening disease. Based on accumulating lines of evidence concerning cancer cells, it was systematically investigated in this project how "the initiation and progression of cancer" are induced in terms of the disorganization of cell and tissue systems in cancer. It was found that abnormalities of cell movement, proliferation, and adhesion in cancer cells play important roles in this disorganization.