Development of an information-intensive basis for cancer chemotherapy

为了支持有新化合物的研究人员，我们通过我们的筛选系统对其化合物(~1000)的生物活性进行了评估，并提供了结果。大多数结果都是在他们同意的情况下公布的。我们开发了“SCADS抑制试剂盒”，这是一个包含300种具有已知作用机制的化合物的库，并将其分发给申请者，以鼓励他们进行化学生物学研究。我们开发了另一个包含200个由研究人员存放的新化合物的图书馆，并将其分发给申请者。我们收集了新的分子靶向抗癌药物的信息，并通过网页提供。

To support researchers who have new compounds, we evaluated biological activities of their compounds (~1000) by our screening system and provided them the results. Most of the results were published with their consent. We developed "SCADS inhibitor kit", a library including 300 compounds with known mechanisms of action, and distributed it to applicants to encourage their chemical biology studies. We developed another library of 200 new compounds deposited by researchers and distributed it to applicants. We collected information on new molecular targeted anticancer drugs and provided it via web pages.