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Analysis of the vertebrate development and regeneration system using medaka genome, EST and mutant resources

Analysis of the vertebrate development and regeneration system using medaka genome, EST and mutant resources
利用青鳉基因组、EST和突变体资源分析脊椎动物发育和再生系统
批准号:
17017003
负责人:
TAKEDA Hiroyuki
金额:
$82.24万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research on Priority Areas
财政年份:
2005
资助国家:
日本
项目状态:
已结题
起止时间:
2005 至 2009

项目摘要

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中文摘要
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英文摘要
The medaka draft genome, together with genomic resources (SNP map, BAC contig, etc.), has been published by the Japanese group in 2007. This greatly facilitated developmental genetics using medaka as a model. In this project, we focused on the medaka developmental mutants isolated by Takeda's and Kudo's laboratories during 2005 to 2009. By the end of this project Takeda and Kudo successfully identified and functionally examined responsible genes for nine mutants (defective in gastrulation, body axes, liver and otolith), and fifteen ones (heart, blood cells, blood vesicle, vertebra, head skeletons, fin morphogenesis and fin regeneration), respectively.
期刊论文(142)
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会议论文
Embryonic origin of osteoblasts in scales and fins of medaka fish
青鳉鱼鳞和鳍中成骨细胞的胚胎起源
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Sabe H., Hashimoto S., Morishige M., Ogawa E., Hashimoto A., Nam J.M., Miura K., Yano H., Onodera Y., Miura K, 加村啓一郎, 島田敦子]
通讯作者: 島田敦子
DOI: 10.1084/jem.20071297
发表时间: 2008-02-18
期刊: The Journal of experimental medicine
影响因子: --
作者: [Shimazaki M, Nakamura K, Kii I, Kashima T, Amizuka N, Li M, Saito M, Fukuda K, Nishiyama T, Kitajima S, Saga Y, Fukayama M, Sata M, Kudo A]
通讯作者: Kudo A
Pkd1l1/Pkd2 as nodal flow sensor to regulate left-right asymmetry
Pkd1l1/Pkd2 作为节点流量传感器调节左右不对称
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Kamura, K.]
通讯作者: K.
A medaka left-right mutant identifies a novel gene responsible for human primary ciliary dvskinesia
青鳉左右突变体鉴定出导致人类原发性睫状运动障碍的新基因
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者: [Takeda, H.]
通讯作者: H.
122
    Assay development for analyzing high performance antibody selection based on cell-free synthesized GPCR proteoliposome.
    • 批准号:
      24710251
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $3.0万
    • 财政年份:
      2012
    • 负责人:
      TAKEDA Hiroyuki
    • 依托单位:
    The machanism of nuclear formation for calcium carbonate biomineralization: the analysis using a medaka mutant
    • 批准号:
      24657146
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.58万
    • 财政年份:
      2012
    • 负责人:
      TAKEDA Hiroyuki
    • 依托单位:
    GENETIC ANALYSIS OF AXIS FORMATION IN VERTEBRATES USING MEDAKA
    • 批准号:
      20247030
    • 项目类别:
      Grant-in-Aid for Scientific Research (A)
    • 资助金额:
      $28.29万
    • 财政年份:
      2008
    • 负责人:
      TAKEDA Hiroyuki
    • 依托单位:
    Analysis of vertebrate left-right axis formation using medaka fish as a model
    • 批准号:
      18370086
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $10.84万
    • 财政年份:
      2006
    • 负责人:
      TAKEDA Hiroyuki
    • 依托单位:
    海外基金