New Catalysed Routes to the Efficient Synthesis of Biologically Active Molecules

高效合成生物活性分子的新催化途径

• 批准号: DP0556759
• 负责人: Prof Barbara Messerle
• 金额: $ 20.43万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2005
• 资助国家: 澳大利亚
• 起止时间: 2005-01-01 至 2008-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0556759
• 关键词: New; Catalysed; Routes; Efficient; Synthesis

Enhancing the economic viability and the energy efficiency of chemical transformations is of fundamental importance in the chemicals industry, and is essential in the targeted production of drugs and fine chemicals for frontier technologies. By using multiple metal centres to simultaneously promote series of reaction steps in a single pot, this project will develop an innovative approach to efficient syntheses of biologically active molecules. The new methods and new catalysts for enhancing the synthesis of highly functionalised compounds will improve significantly the environmental impact of chemical processes by reducing the amount of chemicals required, and reducing waste and energy requirements.

提高化学转化的经济可行性和能源效率在化学工业中具有根本重要性，对于有针对性地生产用于前沿技术的药物和精细化学品至关重要。通过使用多个金属中心在一个锅中同时促进一系列反应步骤，该项目将开发一种有效合成生物活性分子的创新方法。用于增强高度功能化化合物合成的新方法和新催化剂将通过减少所需化学品的数量并减少废物和能源需求来显着改善化学过程对环境的影响。