High resolution ion mobility spectrometer with mass spectrometric detection (IMS-MS)

带质谱检测功能的高分辨率离子淌度谱仪 (IMS-MS)

• 批准号: 502756127
• 金额: --
• 依托单位: Karlsruher Institut für Technologie (KIT)
• 依托单位国家: 德国
• 项目类别: Major Research Instrumentation
• 财政年份: 2022
• 资助国家: 德国
• 起止时间: 2021-12-31 至 无数据
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/502756127?language=en
• 关键词: resolution; ion; mobility; spectrometer; mass

At the university part of the Karlsruhe Institute of Technology (KIT), a high-resolution ion mobility spectrometer with coupled mass spectrometric detection is to be procured . This will allow ion-specific collision cross sections to be determined with high accuracy and compared with the predictions of structural models. This allows mass-selective, structural characterization of large, isolated molecular ions in gas phase. Furthermore, isomer or conformer distributions can be investigated with sufficient collision cross-section resolution. In recent years, there has been a significant technology push in the ion mobility sector, which has led to the availability of instruments that can achieve a collision cross-section resolution of 400 (for parent ions and their charged fragments) while maintaining very high mass resolution. This allows many new molecular chemistry problems to be addressed in gas phase as well as in solution as described in the proposal with examples from inorganic, organic and physical chemistry.

在卡尔斯鲁厄理工学院的大学部分，将采购一台具有耦合质谱检测的高分辨率离子迁移谱仪。这将允许离子特定的碰撞截面被确定与高精度和结构模型的预测进行比较。这允许在气相中对大的、孤立的分子离子进行质量选择性的结构表征。此外，异构体或构象异构体的分布可以调查与足够的碰撞截面分辨率。近年来，离子迁移率领域出现了重大的技术推动，这导致了可以实现400的碰撞截面分辨率（对于母离子及其带电碎片）同时保持非常高的质量分辨率的仪器的可用性。这使得许多新的分子化学问题可以在气相和溶液中得到解决，如提案中所述，例如无机，有机和物理化学。