Role and regulation of specialized metabolites in a permanent plant-bacterium symbiosis

特殊代谢物在永久植物-细菌共生中的作用和调节

• 批准号: 505544272
• 负责人: Dr. Max Crüsemann
• 金额: --
• 依托单位: Institut für Pharmazeutische Biologie
• 依托单位国家: 德国
• 项目类别: Research Grants
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/505544272?language=en
• 关键词: Role; regulation; specialized; metabolites; permanent

Various plant species have evolved permanent or obligate associations with bacteria in their leaves. The synthesis of specialized metabolites by the symbiotic bacteria is a near universal feature of these symbioses. Yet, we know little of the functional roles of these metabolites, or the spatial and temporal signaling events that govern these associations. The objective of RESIDE is to leverage a uniquely tractable leaf symbiosis to test the hypothesis that bacterial metabolism contributes to plant defense against herbivores and competitors. This will be achieved via isolation and characterization of the chemical and molecular signals between the symbiotic partners. The complementary expertise of the French and German groups in the microbiology and natural product chemistry of plant symbioses provide the ideal frame to address the exciting question of how plants control the transmission, colonization and function of microbes at the leaf surface.

各种植物物种已经进化出与其叶子中的细菌永久或专性的联系。共生细菌合成特殊代谢物是这些共生体的一个近乎普遍的特征。然而，我们对这些代谢物的功能作用或控制这些关联的空间和时间信号事件知之甚少。 RESIDE 的目标是利用独特的易处理的叶子共生来检验细菌代谢有助于植物防御食草动物和竞争者的假设。这将通过共生伙伴之间的化学和分子信号的分离和表征来实现。法国和德国研究小组在植物共生的微生物学和天然产物化学方面的互补专业知识为解决植物如何控制叶表面微生物的传播、定殖和功能这一令人兴奋的问题提供了理想的框架。