Elucidating the mechanism of the effects of N-acetyl cysteine on animal models of mental disorders

阐明N-乙酰半胱氨酸对精神障碍动物模型的作用机制

• 批准号: 26860920
• 负责人: Nishikawa Hiromi
• 金额: $ 2.33万
• 依托单位: Kanazawa University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2014
• 资助国家: 日本
• 起止时间: 2014-04-01 至 2016-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-26860920/
• 关键词: 精神疾患; 細胞内システィン; シスチン-グルタミン酸交換体; タンパク質翻訳系; タンパク質分解系; 依存症; 神経可塑性; 細胞内システイン; システイン-グルタミン酸交換体; オートファジー; システィン-グルタミン酸交換体

项目成果

Effectiveness of wildlife-friendly farming on aquatic macroinvertebrate diversity on Sado Island in Japan.

野生动物友好型农业对日本佐渡岛水生大型无脊椎动物多样性的有效性。

• 发表时间: 2015
• 作者: Usio N;Saito R;Akanuma H;Watanabe R
• 通讯作者: Watanabe R

Identification of the learning process and neuronal circuits for instrumental learning in rats

大鼠乐器学习的学习过程和神经元回路的识别

• 发表时间: 2015
• 作者: Shigenobu Toda;Lin Ziquao;Hiromi Nishikawa;Yoshio Iguchi;Bruce T Hope;and Yoshio Minabe
• 通讯作者: and Yoshio Minabe

Pre-stress performance in an instrumental training predicts post-stress behavioral alterations in chronically stressed rats.

• DOI: 10.3389/fnbeh.2015.00119
• 发表时间: 2015
• 期刊: Frontiers in behavioral neuroscience
• 影响因子: 3
• 作者: Iguchi Y;Kosugi S;Lin Z;Nishikawa H;Minabe Y;Toda S
• 通讯作者: Toda S

Repeated exposure of adult rats to transient oxidative stress induces various long-lasting alterations in cognitive and behavioral functions.

• DOI: 10.1371/journal.pone.0114024
• 发表时间: 2014
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Iguchi Y;Kosugi S;Nishikawa H;Lin Z;Minabe Y;Toda S
• 通讯作者: Toda S

c-fos expression may be transiently involved in the transition from goal-directed action to habit in striatal medium spiny neurons while more ubiquitously expressed in striatal astrocytes probably representing goal-directed stage

c-fos表达可能短暂地参与纹状体中型多棘神经元从目标导向行为到习惯的转变，而在纹状体星形胶质细胞中更普遍表达，可能代表目标导向阶段

• 发表时间: 2015
• 作者: Shigenobu Toda;Lin Ziquao;Hiromi Nishikawa;Yoshio Iguchi;Bruce T Hope;and Yoshio Minabe
• 通讯作者: and Yoshio Minabe