Molecular Genetics of Micrbial Pathogenesis

随着我们以小册子的形式准备了该研究小组的详细报告，我们简要地总结了我们的结果如下：表达调控机制已阐明或正在进展的微生物发病机制。志贺氏菌的侵袭-扩散机制。猪霍乱沙门氏菌的SPV毒力。弧菌的溶血素。铜绿假单胞菌的碱性蛋白酶。产气荚膜梭菌的产气荚膜溶血素。粘质沙雷氏菌的菌毛。其激活和/或易位机制已阐明的微生物病原体。铜绿假单胞菌的细胞毒素。霍乱弧菌溶血素，伤寒沙门氏菌Vi抗原。金黄色葡萄球菌TGE溶血素和杀白素。粪肠球菌的溶血素和细菌素。肉毒梭菌C型和E型毒素，其他毒力因子，幽门螺杆菌的尿素酶。肠聚集性大肠埃希菌对人粘膜的粘附性鸡致病性大肠埃希氏菌的自身凝集牙龈卟啉单胞菌的菌丛。拟杆菌神经氨酸酶。R100Trat表达产物提供的血清抵抗力。

As we prepared a report of this research group in detail in a booklet form, we summarized our results briefly as follows.Microbial pathogenesis of which regulatory mechanism of expression is clarified or is progress.The invasion-diffusion mechanisms of shigella bacilli. The spv virulence of Salmonella choleraesuis. The hemolysin of Vibrio species. The alkaline-protease of Pseudomonas aerug. The perfringolysin of Clostridium perfringens. The pili of Seratia marcescens.microbial pathogemesis of which activation and/or translocation mechanism is clarified.The cytotoxin of Pseudomonas aeruginosa. The hemolysin of Vibrio cholerae.The Vi antigen of Salmonella typhi. Tge hemolysin and leukocidin of Staphylococcus aureus. The hemolysin and bacteriocin of Enterococcus faecalis. The type C and E toxins of Clostridium botulinum.Other Virulence factors.The urease of Helicobacter pylori. The adherence of enteroaggregative Escherichia coli to human mucosa. The autoagglutination of chicken pathogenic Escherichia coli. The fimbiae of porphyromonas gingivalis. The neuraminidase of Bacteroides frag. The serum resistance donated by plasmid R100 TraT product.