Nonlinear Dynamics of Pulse Coupled Oscillators

脉冲耦合振荡器的非线性动力学

• 批准号: DP0450673
• 负责人: Prof Adelle Coster
• 金额: $ 14.21万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2004
• 资助国家: 澳大利亚
• 起止时间: 2004-01-31 至 2007-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0450673
• 关键词: Nonlinear; Dynamics; Pulse; Coupled; Oscillators

A mathematical model of the heart pacemaker system will be created, based on simple interacting units. These units have been shown to be good models of physiological information e.g. the discrimination of different influences on heart rate. We will firstly look at the interaction of the units in simple combinations and then tune the model to mimic the behaviour of the cardiac pacemaker. Potential benefits may arise from elucidating the mechanisms underlying arrhythmias which contribute to ?sudden cardiac death? in young men, and suggesting strategies for artificial pacemakers to effectively arrest abnormal rhythms before they convert to potentially fatal fibrillation.

基于简单的相互作用单元，将创建心脏起搏器系统的数学模型。 这些单位已被证明是生理信息的良好模型，例如对心率的不同影响的辨别。 我们将首先研究简单组合中单元的相互作用，然后调整模型以模拟心脏起搏器的行为。 潜在的好处可能会出现从阐明潜在的机制心律失常，这有助于？心脏性猝死在年轻男性中，并建议人工起搏器的策略，以有效地阻止异常节律，然后才转化为潜在的致命性纤维性颤动。