Nano-3D-printer - Upgrade

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The nano-3D printer implemented at Munich University of AppliedSciences in 2014 is currently being used in several research projectsin the field of optical technologies, biofabrication and microfluidics. Asthe first generation of nano-3D printers (2-photon polymerization), ithas a high spatial resolution of about 0.1 μm aber auch eine sehr geringe Schreibgeschwindigkeit. In m but also a very lowwriting speed. As a rule, nano prints take many hours. Forcomplicated objects, several days are not uncommon. In the field ofbiofabrication, this not only limits the number of printed products andthus the number of possible experiments, but also precludes theproduction of complex 3D structures from biological materials such asproteins of the extracellular matrix (ECM) from the outset, as the thebio-resins used do not allow printing times of several days. In the fieldof optical technologies, for example, it has been shown that a vortexwith a 50 μm aber auch eine sehr geringe Schreibgeschwindigkeit. In m diameter fulfills the optical requirements. In order to usethe vortex as an optical element, it would have to have a diameter of500 μm aber auch eine sehr geringe Schreibgeschwindigkeit. In m. Its printing time would be well over a week per component.With this printing time, there is a risk that the photoresists willdegenerate, which on the one hand has a negative impact on the printquality, but also damages the lenses used. Upgrading the nano-3Dprinter with a galvo scan head speeds up the processes by by two tothree orders of magnitude. This reduces the printing time to a fewminutes. This not only increases the number of possible experimentsthat can be carried out, but also reduces the time required for printing.At the same time, larger objects in the range of several hundredmicrometers can be produced with the same surface quality, whichopens new optical applications, for example. In addition, therequested complex 3D scaffold structures from proteins forbiofabrication.This was demonstrated in a feasibility study at the MPIfor Biochemistry in Martinsried. However, detailed investigations arenot possible there because access to the nano-3D printer there isseverely restricted for non-MPI members.