New Methodology for the Stereoselective Construction of Oxygen Heterocycles and Rare Sugar Analogues.

氧杂环和稀有糖类似物立体选择性构建的新方法。

• 批准号: DP0450795
• 负责人: Prof Dennis Taylor
• 金额: $ 21.94万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2004
• 资助国家: 澳大利亚
• 起止时间: 2004-01-01 至 2007-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0450795
• 关键词: New; Methodology; Stereoselective; Construction; Oxygen

The overall goal of this research is to develop new synthetic methods, particularly ones that exhibit high levels of stereocontrol. Current research efforts are directed towards the stereoselective construction of oxygen heterocycles and rare sugar analogues both in their racemic and chiral forms utilising 1,2-dioxines containing tethered hydroxyl moieties as the key chemical precursors. It is envisaged that these investigations will lead to the development of simple experimental protocols for the synthesis of new bioactive organics.

这项研究的总体目标是开发新的合成方法，特别是那些表现出高水平立体控制的方法。目前的研究工作旨在利用含有束缚羟基部分的 1,2-二恶英作为关键化学前体，立体选择性地构建外消旋和手性形式的氧杂环和稀有糖类似物。预计这些研究将导致开发用于合成新生物活性有机物的简单实验方案。