New Methodology for the Stereoselective Construction of Oxygen Heterocycles and Rare Sugar Analogues.
New Methodology for the Stereoselective Construction of Oxygen Heterocycles and Rare Sugar Analogues.
批准号:
DP0450795
负责人:
Prof Dennis Taylor
金额:
$21.94万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2004
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2004-01-01 至 2007-06-30
中文摘要
这项研究的总体目标是开发新的合成方法,特别是那些表现出高水平的立体控制。目前的研究工作是针对氧杂环和稀有糖类似物的外消旋和手性形式的立体选择性建设利用1,2-二氧杂环作为关键的化学前体含有拴羟基部分。据设想,这些调查将导致简单的实验方案的发展,用于合成新的生物活性有机物。
英文摘要
The overall goal of this research is to develop new synthetic methods, particularly ones that exhibit high levels of stereocontrol. Current research efforts are directed towards the stereoselective construction of oxygen heterocycles and rare sugar analogues both in their racemic and chiral forms utilising 1,2-dioxines containing tethered hydroxyl moieties as the key chemical precursors. It is envisaged that these investigations will lead to the development of simple experimental protocols for the synthesis of new bioactive organics.
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