HIGH RESOLUTION MEASUREMENTS OF OPTICAL TOMOGRAPHY IN SCATTERING MEDIUM

散射介质中光学层析成像的高分辨率测量

• 批准号: 09450170
• 负责人: YOSHIMURA Takeaki
• 金额: $ 8.45万
• 依托单位: KOBE UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 1997
• 资助国家: 日本
• 起止时间: 1997 至 1998
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09450170/
• 关键词: tomography; near infrared; 3-D measurement; laser diode; high resolution; optical frequency modulation; tissue; strong scattering medium; 近赤外; 3次元測定; フーリエ変換

Optical coherence tomography based on an optical frequency reflectometry has been developed. The system has been applied to measurements of reflectivity behind chiken tissue. The main results are shown as followings.(1) The optical frequency of tunable laser source can be linearly scanned upto 10 THz during 2 seconds without a mode-hoppe effect.(2) The data processing system with a CCD camera can be time-sequentially stored to memories of 512 frames, and be Fourier-transformed every pixel-data.(3) The depth resolution of this system is 47 mum for five minutes of short analyzing time by using the fast Fourier transform method.(4) The optical system which is constructed of two-lens system is inserted in the Micherlson interferometer. By using this system and an optical heterodyne system, the strong diffuse light from the scattering media was rejected to 10^<-9> of incident light intensity.(5) The system can measure three-dimensionally the reflectivity distribution inside strong scattering media from the surface to the depth of a few millimeters.(6) The reflectivity behind a chiken tissue was measured with measuring time of 2 seconds. From the results, the present system is available to three-dimensional reflectivity distribution measurements.

本文提出了一种基于光学频率反射计的光学相干层析成像。该系统已应用于鸡组织背后反射率的测量。主要结果如下：(1)可调谐激光源的光学频率可以在2秒内线性扫描到10thz，而不存在模希望效应。(2)采用CCD相机的数据处理系统可按时间顺序存储到512帧的存储器中，并对每像素数据进行傅里叶变换。(3)采用快速傅里叶变换方法，在5分钟的短分析时间内，该系统的深度分辨率为47 μ m。(4)在迈克尔逊干涉仪中插入双透镜系统构成的光学系统。利用该系统和光学外差系统，将来自散射介质的强漫射光抑制到入射光强的10^<-9>。(5)该系统可以对强散射介质内部从表面到几毫米深度的反射率分布进行三维测量。(6)测量鸡组织背后的反射率，测量时间为2秒。结果表明，该系统可用于三维反射率分布的测量。

项目成果

吉村 武晃: "光散乱トモグラフィ" 精密工学会誌. 64. 1274-1278 (1998)

Takeaki Yoshimura：“光散射断层扫描”日本精密工程学会杂志 64. 1274-1278 (1998)。

吉村, 将積, 重松: "Imaging a Reflecting Plate Locating in Scattering Media" Optical Review. 4・1B. 221-227 (1997)

Yoshimura、Masazumi、Shigematsu：“对位于散射介质中的反射板进行成像”光学评论 4・1B (1997)。

Hajime Hiratsuka: "Simultaneous measurements of three-dimensional reflectivity distributions in scattering mediabased on optical frequency-domain reflectometry." Opt.Lett.Vol.23, No.18. 1420-1422 (1998)

Hajime Hiratsuka：“基于光学频域反射计同时测量散射介质中的三维反射率分布。”

平塚哉: "Simul taneous measurements of 3-D reflectirity distributins in scattering nedia based on OFDR" Opt.Lett.23,18. 1420-1422 (1998)

Ya Hiratsuka：“基于 OFDR 的散射介质中 3-D 反射率分布的同步测量”Opt.Lett.23,18 (1998)。

吉村武晃: "Optical coherence tomograply in scattering medea using a continuous wave tanable laser dicde" Proc.of SPIE. 3479. 207-214 (1998)

Takeaki Yoshimura：“使用连续波可调谐激光切片进行散射介质的光学相干断层扫描”Proc.of SPIE。 3479. 207-214 (1998)