Development of marine notes in algae.

With a part of research for development of fresh marine notes in algae，following research results obtained. A novel heme protein，which catalyzes oxygenation of polyunsaturated fatty acids affording oxylipins in Chapter I.Bothenantiomers of neodictyoprolene and neodictyoprolenol reminiscent of algae，were successfully obtained by chemoenzymatic synthesesand their attractive olfactory properties were found in Chapter II.The biosynthetic intermediates ofcharacteristic long-chain aldehydes were identified as (2r)-hydrperoxy fatty acids in green algaein Chapter ii . the (Z)-unsaturated dienenals and trienals of cai D217 - D2 and cai D216 - werestereoselectively synthesized and their olfactory evaluation showed a variety of applications inperfume industry in Chapter IV。

With a part of research for development of fresh marine notes in algae, following research results were obtained. A novel heme protein, which catalyzes oxygenation of polyunsaturated fatty acids affording oxylipins in Chapter I.Both enantiomers of neodictyoprolene and neodictyoprolenol reminiscent of algae, were successfully obtained by chemo-enzymatic syntheses, and their attractive olfactory properties were found in Chapter II.The biosynthetic intermediates of characteristic long-chain aldehydes were identified as (2R)-hydrperoxy fatty acids in green algae in Chapter III.The (Z)-unsaturated dienenals and trienals of CィイD217ィエD2 and CィイD216ィエD2 were stereoselectively synthesized and their olfactory evaluation showed a variety of applications in perfume industry in Chapter IV.