Development of marine notes in algae.

藻类海洋香调的开发。

• 批准号: 09556047
• 负责人: KAJIWARA Tadahiko
• 金额: $ 3.07万
• 依托单位: Yamaguchi University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 1997
• 资助国家: 日本
• 起止时间: 1997 至 1999
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09556047/
• 关键词: Aroma components; Flavor; Marine note; Fatty acid; Long-chain aldehyde; Olfactory evaluation; Hydroperoxide; Algae; α-酸化; 精油; 揮発成分; リポキシゲナーゼ; 遺伝子組み換え

With a part of research for development of fresh marine notes in algae, following research results were obtained. A novel heme protein, which catalyzes oxygenation of polyunsaturated fatty acids affording oxylipins in Chapter I.Both enantiomers of neodictyoprolene and neodictyoprolenol reminiscent of algae, were successfully obtained by chemo-enzymatic syntheses, and their attractive olfactory properties were found in Chapter II.The biosynthetic intermediates of characteristic long-chain aldehydes were identified as (2R)-hydrperoxy fatty acids in green algae in Chapter III.The (Z)-unsaturated dienenals and trienals of CィイD217ィエD2 and CィイD216ィエD2 were stereoselectively synthesized and their olfactory evaluation showed a variety of applications in perfume industry in Chapter IV.

本论文通过对海藻中海洋鲜香成分开发的部分研究，取得了以下研究成果。在第一章中，一种新的血红素蛋白，它催化多不饱和脂肪酸的氧化，从而提供氧脂。通过化学-酶促合成，成功地获得了两种使人联想到藻类的对映体neodictyoprolene和neodictyoprolenol，第三章从绿色藻类中鉴定出特征性长链醛类的生物合成中间体为（2 R）-过氧氢脂肪酸。（第四章立体选择性地合成了C_（217）C_（216）C_（217）D_2和C_（216）C_（216）D_2的（Z）-不饱和二烯醛和三烯醛，并对其在香料工业中的应用进行了评价。

项目成果

梶原 忠彦: "海藻バイオフレーバー"化学工業. 49・9. 703-708 (1998)

梶原忠彦：“海藻生物香料”化学工业49・9（1998）。

AKAKABE, Yoshihiko et al: "Odor contribution of volatile compounds of marine algae on seacoast."Jpn. J. Taste Smell Res.. 6. 469-472 (1999)

AKAKABE、Yoshihiko 等人：“海岸海藻挥发性化合物的气味贡献。”Jpn。

赤壁善彦,松井健二,梶原忠彦: "海藻揮発成分の海辺の香りへの寄与について"日本味と匂学会誌. 6・3. 469-472 (1999)

赤部义彦、松井贤二、梶原忠彦：“海藻挥发性成分对海边香气的贡献”日本味觉学会杂志 6・3（1999）。

梶原 忠彦: "沿岸の環境圏(平野敏行監修)「海洋のアメニティーに関する科学」"(株)フジ・テクノシステム、東京. 1389-1393 (1998)

Tadahiko Kajiwara：“沿海环境领域（平野俊之监督）‘海洋设施科学’”Fuji Techno System Co., Ltd.，东京 1389-1393 (1998)。

AKAKABE, Yoshihiko et al: "Highly enantioselective α-hydroperoxylation in Ulva pertusa."Tetrahedon Lett.. 40. 1137-1140 (1999)

AKAKABE、Yoshihiko 等人：“石莼中的高度对映选择性 α-氢过氧化作用。”Tetrahedon Lett.. 40. 1137-1140 (1999)