Pulmorary function test using helical CT

使用螺旋CT进行肺功能检查

• 批准号: 09671394
• 负责人: SAITO Makoto
• 金额: $ 0.9万
• 依托单位: Tokyo Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1997
• 资助国家: 日本
• 起止时间: 1997 至 1999
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09671394/
• 关键词: Pulmonary function; Chest CT; Intrathorasis organs; CT value; Helical CT

We developed pulmonary function test using chest computed tomogram (CT). Previous study using conventional CT showed that CT value form -1024 to -200 HU as A200 indicated total lung volume and CT value from -1024 to -920 HU as A910 indicated total volume of bullous change. EVV (A200-A910) and IVR (A910/A200) also showed an additional information of CT pulmonary test. We also showed these factors by conventional CT could apply to factors by helical CT. Comparison of pulmonary function between spirometry as conventional pulmonary function test and CT pulmonary function test was evaluated in 32 lung cancer cases. Correlation between A910 and FEV1.0, A200 and VC was found (P=0.032). Correlation between A910 and %FEV1.0 (p=0.0118), IVR and V50 (p=0.0227) was also found. Helical CT pulmonary function test provided shorter examination time than conventional CT test (110 minutes vs. 12 minutes) and showed target area as 3D graphics. Comparison of ventilation-perfusion scintigram using SPECT and CT pulmonary function test was evaluated. A little correlation between A200 and SPECT (p=0.053), IVR and SPECT (p=0.05) was found. CT pulmonary function test had additional information of pulmonary function.

我们开发了使用胸部计算机体层摄影(CT)的肺功能测试。以往的常规CT研究表明，A200的CT值在-1024~-200HU之间，A910的CT值在-1024~-920HU之间表示大泡性改变的总体积。EVV(A200-A910)和IVR(A910/A200)也显示了CT肺部检查的附加信息。常规CT的这些因素也可应用于螺旋CT的因素。对32例肺癌患者常规肺功能测定与CT肺功能测定的肺功能进行了比较。A910与FEV1.0、A200与VC呈正相关(P=0.032)。A910与%FEV1.0(p=0.0118)、IVR与V50(p=0.0227)也有相关性。螺旋CT肺功能检查比常规CT检查时间短(110min比12min)，并以3D图形显示靶区。比较SPECT肺功能与CT肺功能显像的异同。A200与SPECT、IVR、SPECT有一定的相关性(P=0.053.0 5)。CT肺功能检查有肺功能的附加信息。

项目成果

斎藤誠: "ヘリカルCTを用いた呼吸機能測定法"Intervision. 8. 57 (1999)

Makoto Saito：“使用螺旋 CT 的呼吸功能测量方法”Intervision。 8. 57 (1999)

斎藤誠: "肺癌診断治療の要点"篠原出版. 141 (1999)

齐藤诚：“肺癌诊断和治疗要点”筱原出版社141（1999）。

Makoto Saito: "Lung Cancer Points for dianosis and treatment"Shinohara Shuppan. (1999)

Makoto Saito：“肺癌诊断和治疗要点”Shinohara Shuppan。

斎藤 誠,他: "肺癌治癒症例における二次発癌の化学予防" 癌治療と宿主. 9. 37-43 (1997)

Makoto Saito 等人：“肺癌治愈病例中继发性癌变的化学预防”《癌症治疗和宿主》9. 37-43 (1997)。

斎藤誠: "CT肺機能測定法"先端医療. 4. 74-75 (1997)

Makoto Saito：《CT 肺功能测量》《高级医学》。4. 74-75 (1997)