Fluorine Levels in Tissues after Administration of Powdered Tea products on the Market.

大量的日本绿茶粉状产品(饮用和食用)含有大量的氟，已经在市场上出现。当然，每天直接食用茶粉会导致芬塔克水平的增加。我们的研究结果表明，茶叶中的酸解性氟通过胃液释放出离子氟，然后被吸收。然而，给药后氟在各组织中的分布还没有完全清楚，本研究的目的是明确茶粉摄入后离子氟在体内的分布。研制了两种只含离子氟的罐头茶产品--绿茶罐头和乌龙茶罐头。为了挽救实验动物，没有设立对照组(仅低F饲料)和商品饲料组，并将本研究的结果与…的结果进行了比较更多的是之前的动物实验。粉茶制品剂量组和罐头茶剂量组之间的平均体重增长没有差异，因此没有认识到由于茶叶类型的差异而产生的影响。无论是粉茶产品组还是罐头茶剂量组，血浆离子氟水平均明显升高。这一结果认为酸性氟向血浆中的转移是离子氟，各剂量组血浆离子氟水平均显著低于商品动物饲料组。股骨、切牙等硬组织中的离子氟水平与血浆中的离子氟水平呈现相同的变化趋势。只有罐装绿茶剂量组硬组织中的离子氟水平与血浆中的离子氟水平呈显著正相关(r=0.85)。各剂量组软组织中离子氟水平均高于对照组和商业动物饲料组。罐头茶制品剂量组软组织中离子氟蓄积量高于茶粉制品剂量组。这一事实表明，以离子F的形式摄入的F的累积可能超过以酸不稳定F的形式摄入的F。在最终证实这一假设的绝对正确性之前，还需要进一步的例子。较少

A lot of powdered products (for drinking and eating) of the Japanese green tea which contains a large amount of fluorine (F), has been come on the market. Of couece, direct eating of powdered tea leaves every day will result in an increased Fintake levels. The results of our research suggested that the acidlabile F in the tea leaves release ionic F by gastric juice, and then is absorbed. The distribution of F in various tissues after the administration of powdered tea products, however, has not been thoroughly clarified.The purpose of the present study was to clealy the distribution of ionic F in the body after ingestion of powdered tea products. Two types of canned tea products containing only ionic F, canned green tea and canned oolong tea, were prepared. In order to save experimental animals, however, neither control group (only low F diet) nor commercial animal diet group were set up, and comparison was made between the results obtained by the present research and those obtained in … More the previous animal experiment.1. The average weight gain showed no differences between the powdered tea products dose groups and the canned tea dose groups, therefore no effects due to the difference in tea types were recognized.2. The increased ionic F levels in plasma was observed in both the powdered tea product groups and the canned tea dose groups. This results considered the transfer of acidlabile F to plasma as ionic F.Ionic F levels in the plasma of all dose groups were significantly showed lower ionic F levels than commercial animal diet group.3. The ionic F levels in hard tissues such as the femur and incisor showed the same tendency as the ionic F levels in plasma. Only the canned green tea dose group demonstrated a significantly remarkable correlation between the ionic F levels in the hard tissue and in the plasma (r=O.85).4. The ionic F levels in soft tissues of all dose groups showed higher than those levels in the control group and commercial animal diet group.S.The accumulation in hard and soft tissues determined in the canned tea product dose groups were higher than the levels of the powdered teaproducts dose groups. This fact suggested the possibility that the accumulation of F ingested in the form of ionic F may exceed that ingested in the form of acid labile F.Further examples are necessary before the absolute validity of this hypothesis is finally confirmed. Less