Fluorine Levels in Tissues after Administration of Powdered Tea products on the Market.

市场上茶粉产品施用后组织中的氟含量。

• 批准号: 09672117
• 负责人: KOYAMA Masahide
• 金额: $ 1.54万
• 依托单位: Showa University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1997
• 资助国家: 日本
• 起止时间: 1997 至 1998
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09672117/
• 关键词: Fluoride; Powdered tea leaves; Animal experiment; Rat; Plasma; Hard tissue; Soft tissue

A lot of powdered products (for drinking and eating) of the Japanese green tea which contains a large amount of fluorine (F), has been come on the market. Of couece, direct eating of powdered tea leaves every day will result in an increased Fintake levels. The results of our research suggested that the acidlabile F in the tea leaves release ionic F by gastric juice, and then is absorbed. The distribution of F in various tissues after the administration of powdered tea products, however, has not been thoroughly clarified.The purpose of the present study was to clealy the distribution of ionic F in the body after ingestion of powdered tea products. Two types of canned tea products containing only ionic F, canned green tea and canned oolong tea, were prepared. In order to save experimental animals, however, neither control group (only low F diet) nor commercial animal diet group were set up, and comparison was made between the results obtained by the present research and those obtained in … More the previous animal experiment.1. The average weight gain showed no differences between the powdered tea products dose groups and the canned tea dose groups, therefore no effects due to the difference in tea types were recognized.2. The increased ionic F levels in plasma was observed in both the powdered tea product groups and the canned tea dose groups. This results considered the transfer of acidlabile F to plasma as ionic F.Ionic F levels in the plasma of all dose groups were significantly showed lower ionic F levels than commercial animal diet group.3. The ionic F levels in hard tissues such as the femur and incisor showed the same tendency as the ionic F levels in plasma. Only the canned green tea dose group demonstrated a significantly remarkable correlation between the ionic F levels in the hard tissue and in the plasma (r=O.85).4. The ionic F levels in soft tissues of all dose groups showed higher than those levels in the control group and commercial animal diet group.S.The accumulation in hard and soft tissues determined in the canned tea product dose groups were higher than the levels of the powdered teaproducts dose groups. This fact suggested the possibility that the accumulation of F ingested in the form of ionic F may exceed that ingested in the form of acid labile F.Further examples are necessary before the absolute validity of this hypothesis is finally confirmed. Less

含有大量氟（F）的日本绿色茶的许多粉末产品（用于饮用和食用）已经上市。当然，每天直接食用粉末茶叶会导致Fintake水平增加。结果表明，茶叶中的酸不稳定氟经胃液释放出离子型氟，然后被吸收。然而，摄入粉末茶制品后，F在各组织中的分布尚未完全阐明，本研究的目的是明确摄入粉末茶制品后，离子F在体内的分布。制备了两种仅含离子F的罐装茶产品，即罐装绿色茶和罐装乌龙茶。为节省实验动物，未设对照组（低氟饲料）和商品饲料组，并将本研究结果与 ...更多信息 动物实验1.平均体重增加显示粉末茶产品剂量组和罐装茶剂量组之间没有差异，因此没有识别到由于茶类型差异引起的影响。在粉末茶产品组和罐装茶剂量组中均观察到血浆中离子F水平升高。这一结果认为酸不稳定F以离子F的形式转移到血浆中，各剂量组血浆中离子F水平均显著低于市售饲料组.股骨和切牙等硬组织中的离子F水平与血浆中的离子F水平呈现相同的趋势。只有罐装绿色茶剂量组的硬组织和血浆中的离子F水平之间存在显著的相关性（r= 0.85）.各剂量组软组织中氟离子含量均高于对照组和市售饲料组。罐装茶制品剂量组硬组织和软组织中氟离子含量均高于粉末茶制品剂量组。这一事实表明的可能性，即积累的F摄入的形式离子F可能超过摄入的形式酸不稳定的F.进一步的例子是必要的，这一假设的绝对有效性之前，最终得到证实。少

项目成果

Masahide KOYAMA,et al.: "Fluoride release from powdered tea leaves treated with artificial gastric and intestinal juices." The Journal of Showa University Dental Society. Vol.18, No.2. 174-182 (1998)

Masahide KOYAMA 等人：“用人工胃和肠液处理的茶叶粉中氟化物的释放。”

古山公英ほか: "粉末茶からの人工胃液及び腸液によるフッ素溶出の検討" 昭和歯学会雑誌. 18・2. 174-182 (1998)

Kimie Furuyama等人：“使用人工胃和肠液从粉末茶中洗脱氟化物的研究”昭和牙科学会杂志18・2（1998）。