Intemational strategy for the innovation in electroanalysis

本项目以相互访问的方式开展国际合作研究工作，每两年共访问25次。作为结果的具体例子，我们与R. L. McCreery教授小组一起，使用拉曼光谱对电极表面沉积的材料进行了纳米分析。因此，在拉曼观察的基础上，澄清了金属阳离子还原TCNQ过程中导电固体的沉积机制。此外，与R. G. Compton教授合作，建立了微带电极阵列通道流动伏安法纳米电分析技术。结果表明，该方法对电极反应机理的澄清以及微量物质的检测是非常有效的。与H. Kim教授一起，我们研究了使用杯状[4]芳烃衍生物作为金属阳离子离子载体的纳米分析。通过流动电解、紫外可见和ESR等方法的研究，明确了两种醌衍生物的包合行为。与Y. B. Shim教授合作，研究了苯醌衍生物在脂质修饰电极上的电极反应。阐明了电生成阴离子自由基在纳米空间上对电极表面的稳定作用，以及脂质烷基链长度对其稳定性的影响。与R. E. Sioda教授一起，研究了柱电解法检测痕量物质的理论问题。此外，与Y. Bohari教授一起，为了阐明电子转移反应的分子方面，分析了二茂铁衍生物的电化学行为。

In the present project, international cooperative research work was carried out through the visiting each other, whose total times was 25 times per two years.As concrete examples of the results, with Prof. R. L. McCreery group, we performed nano-analysis of the deposited materials on the electrode surfaces using Raman spectroscopy. Consequently, on the basis of the Raman observations, the deposition mechanism of the conducted solids was clarified in the reduction of TCNQ with metal cations. In addition, with Prof. R. G. Compton, nano-electroanalytical technique was established using micro-band electrodes array with channel flow voltammetry. It was found that this approach is very effective in the clarification of the mechanistic aspects of the electrode reactions as well as the detection of trace materials.With Prof. H. Kim, we examined nano-analysis using calix[4]arene derivatives as an ionophore for metal cations. The specific inclusion behavior of the two quinone derivatyives was clarified through the cooperative research using flow-electrolysis UV-vis and ESR measurements. Also, with Prof. Y. B. Shim, we examined the electrode reactions of benzoquinone derivatives on lipid modified electrodes. Stabilization of the electrogenerated anion radical in the nano-space onto the electrode surface was clarified, together with the effects of alkyl chain length of the lipids on it. With Prof. R. E. Sioda, theoretical aspects of a column electrolysis method were studied for the detection of trace materials. In addition, with Prof. Y. Bohari, to clarify the molecular aspects of the electron transfer reactions, the electrochemical behaviors of ferrocene derivatives were analyzed.