Development of colitic mucosa repair therapy by the induction of regeneration-specific stem cell niche formation
Development of colitic mucosa repair therapy by the induction of regeneration-specific stem cell niche formation
批准号:
25293170
负责人:
Okamoto Ryuichi
金额:
$11.81万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2013
资助国家:
日本
项目状态:
已结题
起止时间:
2013-04-01 至 2016-03-31
中文摘要
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英文摘要
期刊论文(38)
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Notch signaling regulates expression of Bestrophin-4, a novel enterocyte-specific HCO3-/Cl- channel, in human intestinal epithelial cells.
Notch 信号传导调节人肠上皮细胞中 Bestropin-4(一种新型肠细胞特异性 HCO3-/Cl- 通道)的表达。
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[Go Ito, Ryuichi Okamoto, Satoru Fujii, Hiromichi Shimizu, Tatsuro Murano, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe]
通讯作者:
Mamoru Watanabe
DOI:
10.1111/cas.12703
发表时间:
2015-08
期刊:
Cancer science
影响因子:
5.7
作者:
[Fukushima K, Tsuchiya K, Kano Y, Horita N, Hibiya S, Hayashi R, Kitagaki K, Negi M, Itoh E, Akashi T, Eishi Y, Oshima S, Nagaishi T, Okamoto R, Nakamura T, Watanabe M]
通讯作者:
Watanabe M
Enrichment of Intestinal Stem Cells by the 3D-Culture of IBD Patient Derived Intestinal epithelium.
通过 IBD 患者来源的肠上皮的 3D 培养富集肠干细胞。
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[Kohei Suzuki, Satoru Fujii, Toru Nakata, Ami Kawamoto, Fumiaki Ishibashi, Sayaka Ohashi Segawa, Tomohiro Mizutani, Kiichiro Tsuchiya, Kazuo Otsuka,Tetsuya Nakamura, Ryuichi Okamoto, M. Watanabe]
通讯作者:
M. Watanabe
Distinct Role of Notch Ligands, DLL1 and Dll4, in Normal and in Tumor Intestinal Epithelium.
Notch 配体 DLL1 和 Dll4 在正常和肿瘤肠上皮中的独特作用。
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[Toru Nakata, Hiromichi Shimizu, Kohei Suzuki, Satoru Fujii, Go Ito, Kiichiro Tsuchiya, Tetsuya Nakamura, Ryuichi Okamoto, Katsuto Hozumi, Mamoru Watanabe.]
通讯作者:
Mamoru Watanabe.
DOI:
10.1371/journal.pone.0088369
发表时间:
2014
期刊:
PloS one
影响因子:
3.7
作者:
[Suzuki M, Nagaishi T, Yamazaki M, Onizawa M, Watabe T, Sakamaki Y, Ichinose S, Totsuka M, Oshima S, Okamoto R, Shimonaka M, Yagita H, Nakamura T, Watanabe M]
通讯作者:
Watanabe M
共 28 条
Development of primitive-gut-derived organ bioengineering methods based on spheroid designing.
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批准号:20K21597
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项目类别:Grant-in-Aid for Challenging Research (Exploratory)
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资助金额:$4.16万
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财政年份:2020
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负责人:Okamoto Ryuichi
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依托单位:
Identification and functional analysis of colonic label-retaining goblet cells for the application to regeneration of the inflamed mucosa.
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批准号:19H03634
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.23万
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财政年份:2019
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负责人:Okamoto Ryuichi
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依托单位:
Theoretical study of steric effects in electrolyte solutions: Toward thorough understanding of Hofmester effect
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批准号:18K03562
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.66万
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财政年份:2018
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负责人:Okamoto Ryuichi
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依托单位:
Analysis and therapeutic application of intestinal epithelial cell plasticity in inflammatory bowel disease
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批准号:16H05284
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.07万
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财政年份:2016
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负责人:Okamoto Ryuichi
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依托单位:
Establishment of enterohormone farm by using cultured human intestinal epithelial cells
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批准号:15K15286
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
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财政年份:2015
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负责人:Okamoto Ryuichi
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依托单位:
海外基金