Development of colitic mucosa repair therapy by the induction of regeneration-specific stem cell niche formation
通过诱导再生特异性干细胞生态位形成开发结肠粘膜修复疗法
基本信息
- 批准号:25293170
- 负责人:
- 金额:$ 11.81万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (B)
- 财政年份:2013
- 资助国家:日本
- 起止时间:2013-04-01 至 2016-03-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
项目成果
期刊论文数量(38)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Atonal homolog 1 protein stabilized by tumor necrosis factor α induces high malignant potential in colon cancer cell line.
- DOI:10.1111/cas.12703
- 发表时间:2015-08
- 期刊:
- 影响因子:5.7
- 作者:Fukushima K;Tsuchiya K;Kano Y;Horita N;Hibiya S;Hayashi R;Kitagaki K;Negi M;Itoh E;Akashi T;Eishi Y;Oshima S;Nagaishi T;Okamoto R;Nakamura T;Watanabe M
- 通讯作者:Watanabe M
Notch signaling regulates expression of Bestrophin-4, a novel enterocyte-specific HCO3-/Cl- channel, in human intestinal epithelial cells.
Notch 信号传导调节人肠上皮细胞中 Bestropin-4(一种新型肠细胞特异性 HCO3-/Cl- 通道)的表达。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:Go Ito;Ryuichi Okamoto;Satoru Fujii;Hiromichi Shimizu;Tatsuro Murano;Kiichiro Tsuchiya;Tetsuya Nakamura;Mamoru Watanabe
- 通讯作者:Mamoru Watanabe
Enrichment of Intestinal Stem Cells by the 3D-Culture of IBD Patient Derived Intestinal epithelium.
通过 IBD 患者来源的肠上皮的 3D 培养富集肠干细胞。
- DOI:
- 发表时间:2015
- 期刊:
- 影响因子:0
- 作者:Kohei Suzuki;Satoru Fujii;Toru Nakata;Ami Kawamoto;Fumiaki Ishibashi;Sayaka Ohashi Segawa;Tomohiro Mizutani;Kiichiro Tsuchiya;Kazuo Otsuka,Tetsuya Nakamura;Ryuichi Okamoto;M. Watanabe
- 通讯作者:M. Watanabe
Distinct expression patterns of Notch ligands, Dll1 and Dll4, in normal and inflamed mice intestine.
- DOI:10.7717/peerj.370
- 发表时间:2014
- 期刊:
- 影响因子:2.7
- 作者:Shimizu H;Okamoto R;Ito G;Fujii S;Nakata T;Suzuki K;Murano T;Mizutani T;Tsuchiya K;Nakamura T;Hozumi K;Watanabe M
- 通讯作者:Watanabe M
Myosin light chain kinase expression induced via tumor necrosis factor receptor 2 signaling in the epithelial cells regulates the development of colitis-associated carcinogenesis.
- DOI:10.1371/journal.pone.0088369
- 发表时间:2014
- 期刊:
- 影响因子:3.7
- 作者:Suzuki M;Nagaishi T;Yamazaki M;Onizawa M;Watabe T;Sakamaki Y;Ichinose S;Totsuka M;Oshima S;Okamoto R;Shimonaka M;Yagita H;Nakamura T;Watanabe M
- 通讯作者:Watanabe M
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Okamoto Ryuichi其他文献
Recommendations (Proposal) for promoting research for overcoming neurological diseases 2020
2020年促进攻克神经系统疾病研究的建议(提案)
- DOI:
10.5692/clinicalneurol.cn-001695 - 发表时间:
2022 - 期刊:
- 影响因子:0
- 作者:
Takahashi Junichi;Mizutani Tomohiro;Sugihara Hady Yuki;Nagata Sayaka;Kato Shu;Hiraguri Yui;Takeoka Sayaka;Tsuchiya Mao;Kuno Reiko;Kakinuma Sei;Watanabe Mamoru;Okamoto Ryuichi;望月秀樹,青木正志,池中建介,井上治久,岩坪威,宇川義一,岡澤均,小野賢二郎,小野寺理,北川一夫,齊藤祐子,下畑享良,髙橋良輔,戸田達史,中原仁,松本理器,水澤英洋,三井純,村山繁雄,勝野雅央,日本神経学会将来構想委員会,青木吉嗣,石浦浩之,和泉唯信,小池春樹,島田斉,髙橋祐二,徳田隆彦,中嶋秀人,波田野琢,三澤園子,渡辺宏久 - 通讯作者:
望月秀樹,青木正志,池中建介,井上治久,岩坪威,宇川義一,岡澤均,小野賢二郎,小野寺理,北川一夫,齊藤祐子,下畑享良,髙橋良輔,戸田達史,中原仁,松本理器,水澤英洋,三井純,村山繁雄,勝野雅央,日本神経学会将来構想委員会,青木吉嗣,石浦浩之,和泉唯信,小池春樹,島田斉,髙橋祐二,徳田隆彦,中嶋秀人,波田野琢,三澤園子,渡辺宏久
Fluctuating hydrodynamics of dilute electrolyte solutions: systematic perturbation calculation of effective transport coefficients governing large-scale dynamics
稀电解质溶液的脉动流体动力学:控制大尺度动力学的有效输运系数的系统摄动计算
- DOI:
10.1088/1742-5468/ac8c8d - 发表时间:
2022 - 期刊:
- 影响因子:0
- 作者:
Sumi Tomonari;Harada Kouji;鎌原勇太;原田勝孝;Okamoto Ryuichi - 通讯作者:
Okamoto Ryuichi
Protein hydration dynamics probed by broadband dielectric spectroscopy and neutron scattering
通过宽带介电谱和中子散射探测蛋白质水合动力学
- DOI:
- 发表时间:
2020 - 期刊:
- 影响因子:0
- 作者:
Katsuto Hiroyuki;Okamoto Ryuichi;Sumi Tomonari;Koga Kenichiro;Naoki Yamamoto - 通讯作者:
Naoki Yamamoto
State cyclone of a micromachine driven by catalytic reaction
催化反应驱动微机械状态旋风分离器
- DOI:
- 发表时间:
2021 - 期刊:
- 影响因子:0
- 作者:
Yasuda Kento;Okamoto Ryuichi;Komura Shigeyuki;Kento Yasuda and Shigeyuki Komura - 通讯作者:
Kento Yasuda and Shigeyuki Komura
Ramucirumab (RAM) as second-line treatment in patients with advanced hepatocellular carcinoma (HCC) and elevated baseline α-fetoprotein (AFP): an analysis of AFP kinetics in the phase 3 REACH-2 study.
Ramucirumab (RAM) 作为二线治疗晚期肝细胞癌 (HCC) 和基线甲胎蛋白 (AFP) 升高的患者:3 期 REACH-2 研究中 AFP 动力学分析。
- DOI:
- 发表时间:
2019 - 期刊:
- 影响因子:0
- 作者:
Kuno Reiko;Ito Go;Kawamoto Ami;Hiraguri Yui;Sugihara Hady Yuki;Takeoka Sayaka;Nagata Sayaka;Takahashi Junichi;Tsuchiya Mao;Anzai Sho;Mizutani Tomohiro;Shimizu Hiromichi;Yui Shiro;Oshima Shigeru;Tsuchiya Kiichiro;Watanabe Mamoru;Okamoto Ryuichi;Kudo Masatoshi - 通讯作者:
Kudo Masatoshi
Okamoto Ryuichi的其他文献
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{{ truncateString('Okamoto Ryuichi', 18)}}的其他基金
Development of primitive-gut-derived organ bioengineering methods based on spheroid designing.
基于球体设计的原始肠源器官生物工程方法的发展。
- 批准号:
20K21597 - 财政年份:2020
- 资助金额:
$ 11.81万 - 项目类别:
Grant-in-Aid for Challenging Research (Exploratory)
Identification and functional analysis of colonic label-retaining goblet cells for the application to regeneration of the inflamed mucosa.
结肠标记保留杯状细胞的鉴定和功能分析,用于发炎粘膜的再生。
- 批准号:
19H03634 - 财政年份:2019
- 资助金额:
$ 11.81万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Theoretical study of steric effects in electrolyte solutions: Toward thorough understanding of Hofmester effect
电解质溶液中空间效应的理论研究:全面理解霍夫梅斯特效应
- 批准号:
18K03562 - 财政年份:2018
- 资助金额:
$ 11.81万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Analysis and therapeutic application of intestinal epithelial cell plasticity in inflammatory bowel disease
肠上皮细胞可塑性分析及其在炎症性肠病中的治疗应用
- 批准号:
16H05284 - 财政年份:2016
- 资助金额:
$ 11.81万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Establishment of enterohormone farm by using cultured human intestinal epithelial cells
利用培养人肠上皮细胞建立肠激素农场
- 批准号:
15K15286 - 财政年份:2015
- 资助金额:
$ 11.81万 - 项目类别:
Grant-in-Aid for Challenging Exploratory Research
相似海外基金
炎症性腸疾患の腸管上皮におけるNotchシグナル制御機構の解明と新規治療法開発
炎症性肠病肠上皮Notch信号调控机制的阐明及新疗法的开发
- 批准号:
19K17454 - 财政年份:2019
- 资助金额:
$ 11.81万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
The Role of Dendritic Cells on the Intestinal Stem Cell Niche
树突状细胞对肠干细胞生态位的作用
- 批准号:
17K15717 - 财政年份:2017
- 资助金额:
$ 11.81万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
Analysis of intestinal mucosal repair by Notch-activated stem cells
Notch激活干细胞对肠粘膜修复的分析
- 批准号:
23790777 - 财政年份:2011
- 资助金额:
$ 11.81万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
Analysis of maintenance and repair mechanism of the intestinal mucosa by the Notch ligand-receptor system
Notch配体-受体系统对肠黏膜的维护和修复机制分析
- 批准号:
23790776 - 财政年份:2011
- 资助金额:
$ 11.81万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
Analysis of Notch-mediated regeneration of the intestinal epithelia
Notch介导的肠上皮再生分析
- 批准号:
21790651 - 财政年份:2009
- 资助金额:
$ 11.81万 - 项目类别:
Grant-in-Aid for Young Scientists (B)