Establishment of enterohormone farm by using cultured human intestinal epithelial cells
Establishment of enterohormone farm by using cultured human intestinal epithelial cells
批准号:
15K15286
负责人:
Okamoto Ryuichi
金额:
$2.33万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2015
资助国家:
日本
项目状态:
已结题
起止时间:
2015-04-01 至 2017-03-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
期刊论文(14)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
Contiuous stimulation with cytokines leads to irreversible activation of NF-γb signaling in colonic epithelial cells by organoid culture.
通过类器官培养,细胞因子的持续刺激会导致结肠上皮细胞中 NF-γb 信号不可逆的激活。
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[Shuji Hibiya, Kiichiro Tsuchiya, Tomoaki Shirasaki, Keita Fukushima, Ryohei Hayashi, Nobukatsu Horita, Shigeru Oshima ,Ryuichi Okamoto, Tetsuya Nakamura,Mamoru Watanabe]
通讯作者:
Tetsuya Nakamura,Mamoru Watanabe
Distinct Role of Notch Ligands, DLL1 and Dll4, in Normal and in Tumor Intestinal Epithelium.
Notch 配体 DLL1 和 Dll4 在正常和肿瘤肠上皮中的独特作用。
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[Toru Nakata, Hiromichi Shimizu, Kohei Suzuki, Satoru Fujii, Go Ito, Kiichiro Tsuchiya, Tetsuya Nakamura, Ryuichi Okamoto, Katsuto Hozumi, Mamoru Watanabe.]
通讯作者:
Mamoru Watanabe.
Continuous Stimulation With Cytokines Leads to Irreversible Accumulation of NF-kB Signaling in Colonic Epithelial Cells.
细胞因子的持续刺激会导致结肠上皮细胞中 NF-kB 信号不可逆的积累。
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[Shuji Hibiya, Kiichiro Tsuchiya, Keita Fukushima, Ryohei Hayashi, Nobukatsu Horita, Shigeru Oshima, Ryuichi Okamoto, Tetsuya Nakamura, M. Watanabe]
通讯作者:
M. Watanabe
A novel fluorescent labelling system into small intestinal organoid reveals independent long-lived intestinal stem cells in a crypt.
小肠类器官中的新型荧光标记系统揭示了隐窝中独立的长寿命肠干细胞。
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[Nobuyuki Horita, Kiichiro Tsuchiya, Ryohei Hayashi, Keita Fukushima, Shuji Hibiya, Masayoshi Fukuda, Tomohiro Mizutani, Ryuichi Okamoto, Testuya Nakamura and M. Watanabe]
通讯作者:
Testuya Nakamura and M. Watanabe
In vitro organoid model reveals PGE2 as a robust mediator of chloride & water secretion by human intestinal epithelial cells
体外类器官模型揭示 PGE2 是氯离子的强大介质
DOI:
--
发表时间:
2016
期刊:
影响因子:
--
作者:
[Satoru Fujii, Kohei Suzuki, Ami Kawamoto, Fumiaki Ishibashi, Toru Nakata, Go Ito, Hiromichi Shimizu, Tomohiro Mizutani, Kiichiro Tsuchiya, Tetsuya Nakamura, Kazuo Ohtsuka, Ryuichi Okamoto, Mamoru Watanabe]
通讯作者:
Mamoru Watanabe
共 9 条
Development of primitive-gut-derived organ bioengineering methods based on spheroid designing.
-
批准号:20K21597
-
项目类别:Grant-in-Aid for Challenging Research (Exploratory)
-
资助金额:$4.16万
-
财政年份:2020
-
负责人:Okamoto Ryuichi
-
依托单位:
Identification and functional analysis of colonic label-retaining goblet cells for the application to regeneration of the inflamed mucosa.
-
批准号:19H03634
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.23万
-
财政年份:2019
-
负责人:Okamoto Ryuichi
-
依托单位:
Theoretical study of steric effects in electrolyte solutions: Toward thorough understanding of Hofmester effect
-
批准号:18K03562
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.66万
-
财政年份:2018
-
负责人:Okamoto Ryuichi
-
依托单位:
Analysis and therapeutic application of intestinal epithelial cell plasticity in inflammatory bowel disease
-
批准号:16H05284
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.07万
-
财政年份:2016
-
负责人:Okamoto Ryuichi
-
依托单位:
Development of colitic mucosa repair therapy by the induction of regeneration-specific stem cell niche formation
-
批准号:25293170
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.81万
-
财政年份:2013
-
负责人:Okamoto Ryuichi
-
依托单位:
海外基金