权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Computer Simulation on the Amelogenesis: Three-dimensional Relationship between the enamel structure and Ameloblasts.

釉质生成的计算机模拟：釉质结构与成釉细胞之间的三维关系。

基本信息

批准号：
60440082
负责人：
WAKITA Minoru
金额：
$ 15.17万
依托单位：
Hokkaido University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (A)
财政年份：
1985
资助国家：
日本
起止时间：
1985 至 1987
项目状态：
已结题

项目摘要

The structural and embryological relationships between ameloblasts and crystallite arrangement were studied on the tooth germ in dog and cat. Under the scanning electron microscope, the three dimensional structure of the Tomes' processes can be envisaged as the upper part of a diagonally cut column. Each of them is constructed by two crescent faces. One is generally flat (S-face) and the other is curved (N-face). The S-face faces to the forming end of the prism and the N-face to the adjacent prism or the interprismatic substances.The crystallites arrange perpendicularly to the S-face and the free surface of ameloblasts which is the area among Tomes' processes and is adjacent to the forming surface of developing enamel. The N-face is only the sliding face of the Tomes' processes.In dog, the structural change of Tomes' processes during amelogenesis were studied by SEM and TEM. Most of processes has the form envisaged as the upper part of a diagonally cut column, but processes forming outer layer of enamel appear the stump-like structure in three dimension. It was concluded from these observations and discussions as follwed. The contour and surface structure of the S-face decides the cross-sectional structure of a prism and the crystallite arrangement pattern in an enamel respectively. And the arrangement of Tomes' processes decides the prism pattern in the enamel. Crystallite arranged on the S-face form the enamel prism, and those on the free surface of ameloblasts form the interprismatic substance.These results were examined by the computer simulation. The displayed crystallite arrangements after simulation represented the same crystallite attangementpattern seen in the natural enamel. The relationships between ameloblasts and enamel structure proposed by us were objectively confirmed.

本文研究了狗、猫牙胚成釉细胞与牙胚微晶排列的结构和胚胎学关系。在扫描电镜下，Tomes突的三维结构可设想为一个斜截柱的上部。每一个都是由两个月牙面构成的。一个通常是平坦的（S面），另一个是弯曲的（N面）。S面朝向棱柱的形成端，N面朝向相邻棱柱或棱柱间物质，微晶垂直于S面和Tomes突之间的成釉细胞自由面排列，与发育中釉质的形成面相邻。本实验用扫描电镜和透射电镜研究了犬牙釉质形成过程中Tomes突的结构变化。大多数突起的形状被设想为斜向切割的柱的上部，但形成釉质外层的突起在三维上呈现树桩状结构。从这些观察和讨论中得出以下结论。S面的轮廓和表面结构分别决定了牙釉质中棱柱的截面结构和微晶的排列方式。托姆斯突起的排列决定了釉质中的棱柱图案。排列在成釉细胞S面的微晶形成釉棱柱，而排列在成釉细胞游离面的微晶形成釉棱柱间质。模拟后显示的微晶排列代表了与天然釉质中相同的微晶排列模式。客观地证实了我们提出的成釉细胞与釉质结构的关系。