The role of radiation therapy in the management of malignantlymphoma

放射治疗在恶性淋巴瘤治疗中的作用

• 批准号: 61304048
• 负责人: MASAKI Norie
• 金额: $ 2.56万
• 依托单位: Osaka University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Co-operative Research (A)
• 财政年份: 1986
• 资助国家: 日本
• 起止时间: 1986 至 1987
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-61304048/
• 关键词: Malignant lymphoma; Hodgkin's disease; Non-Hodgkin's lymphoma; Radiation therapy; Radiotherapy combined with chemotherapy; 頭頚部のリンパ腫; 放射線冶療; 化学療法; 頭頸部のリンパ腫

A multi-institutional study of 1514 patients with non-Hodgkin's lymphoma and 234 patients with Hodgkin's disease treated between 1972 and 1985 was performed. Of 845 patients with non-Hodgkin's lymphoma localized in the head and neck, radiation therapy had significant responses and 95% of local control rate in the treated region. Howeer, since 27% of stage I and 52% of stage II patients experienced relapse in the distant sites, five year survival were 65% for stage I patients and 46% for stage II. Of these, 54% of patients were treated with radiation therapy alone, and the others were treated radiation combined with chemotherapy. There were no significant difference of survival between two groups.

对1972年至1985年间治疗的1514例非霍奇金淋巴瘤和234例霍奇金病患者进行了多机构研究。845例头颈部非何杰金淋巴瘤患者，放射治疗有显著疗效，局部控制率达95%。然而，由于27%的I期和52%的II期患者在远处复发，因此I期患者的5年生存率为65%，II期为46%。其中，54%的患者单独接受放射治疗，其他患者接受放射联合化疗。两组患者的生存率差异无统计学意义。

项目成果

尾山 淳: 癌の臨床. 34.5. (1988)

Jun Oyama：癌症临床实践34.5（1988）。

Masaki, N., et al.: "Treatment results of radiation therapy for patients with stage II non-Hodgkin's lymphoma of Walderer's ring." New Med. 42. 1536-1537 (1987)

Masaki, N. 等人：“II 期瓦德勒环非霍奇金淋巴瘤患者放射治疗的治疗结果。”

池田恢: 癌の臨床. 32. 225-233 (1986)

Ikeda, T.：癌症临床实践。32. 225-233 (1986)

早渕尚文: 癌の臨床. 33. 13-20 (1987)

Naofumi Hayabuchi：临床癌症。33. 13-20 (1987)

Watanabe, S., et al.: "Late relapse of non-Hodgkin's lymphoma primarily treated by radiation therapy. A report of the Japanese Lymphoma Radiation Therapy Study Group(JLRTG)." Jap J Cancer Clin. 34. (1988)

Watanabe, S. 等人：“主要通过放射治疗治疗的非霍奇金淋巴瘤晚期复发。日本淋巴瘤放射治疗研究组 (JLRTG) 的报告。”